• Influence of Protein Carbonylation on Human Adipose Tissue Dysfunction in Obesity and Insulin Resistance 

      Navarro-Ruiz, Carmen; Soler-Vázquez, M. Carmen; Díaz-Ruiz, Alberto; Peinado, Juan R.; Nieto Calonge, Andrea; Sánchez Ceinos, Julia; Tercero-Alcázar, C.; López-Alcalá, J.; Rangel Zúñiga, Oriol Alberto; Membrives, Antonio; López-Miranda, José; Malagón, María M.; Gúzman-Ruiz, Rocío (MDPI, 2022)
      Background: Obesity is characterized by adipose tissue dysregulation and predisposes individuals to insulin resistance and type 2 diabetes. At the molecular level, adipocyte dysfunction has been linked to obesity-triggered ...
    • Nutritional, hormonal, and depot-dependent regulation of the expression of the small GTPase Rab18 in rodent adipose tissue 

      Pulido, Marina R.; Rabanal Ruiz, Yoana; Almabouada, Farid; Díaz-Ruiz, Alberto; Burrel, María A; Vázquez, María J.; Castaño, Justo P.; Kineman, Rhonda D.; Luque, Raúl M.; Diéguez, Carlos; Vázquez-Martínez, Rafael; Malagón, María M. (Society for Endocrinology, 2013)
      There is increasing evidence that proteins associated with lipid droplets (LDs) play a key role in the coordination of lipid storage and mobilization in adipocytes. The small GTPase, RAB18, has been recently identified as ...
    • Rab18 dynamics in adipocytes in relation to lipogenesis, lipolysis and obesity 

      Pulido, Marina R.; Díaz-Ruiz, Alberto; Jiménez-Gómez, Yolanda; García Navarro, S.; Gracia-Navarro, F.; Tinahones, Francisco J.; López-Miranda, José; Frühbeck, Gema; Vázquez Martínez, Rafael; Malagón, María M. (PLOS, 2011)
      Lipid droplets (LDs) are organelles that coordinate lipid storage and mobilization, both processes being especially important in cells specialized in managing fat, the adipocytes. Proteomic analyses of LDs have consistently ...