Listar por autor "907c75cc-ea5e-478c-bef8-b9a20f3617ee"
Mostrando ítems 1-3 de 3
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Comparative Cytotoxic Activity of Hydroxytyrosol and Its Semisynthetic Lipophilic Derivatives in Prostate Cancer Cells
León González, A.J.; Sáez Martínez, Prudencio; Jiménez-Vacas, J.M.; Herrero-Aguayo, V.; Montero-Hidalgo, Antonio J.; Gómez Gómez, Enrique; Madrona, Andrés; Castaño, Justo P.; Espartero, José L.; Gahete Ortiz, Manuel D.; Luque, Raúl M. (MDPI, 2021)A high adherence to a Mediterranean diet has been related to numerous beneficial effects in human health, including a lower incidence and mortality of prostate cancer (PCa). Olive oil is an important source of phenolic ... -
Oncogenic Role of Secreted Engrailed Homeobox 2 (EN2) in Prostate Cancer
Gómez-Gómez, E.; Jiménez-Vacas, J.M.; Pedraza-Arévalo, Sergio; López-López, F.; Herrero-Aguayo, V.; Hormaechea Agulla, Daniel; Valero-Rosa, J.; Ibáñez-Costa, Alejandro; León González, A.J.; Sánchez-Sánchez, Rafael; Gónzalez Serrano, T.; Requena-Tapia, M.J.; Castaño, Justo P.; Carrasco-Valiente, J.; Gahete Ortiz, Manuel D.; Luque, Raúl M. (MDPI, 2019)Engrailed variant-2 (EN2) has been suggested as a potential diagnostic biomarker; however, its presence and functional role in prostate cancer (PCa) cells is still controversial or unknown. Here, we analyzed 1) the ... -
Unleashing the Diagnostic, Prognostic and Therapeutic Potential of the Neuronostatin/GPR107 System in Prostate Cancer
Sáez Martínez, Prudencio; Jiménez-Vacas, J.M.; León González, A.J.; Herrero-Aguayo, V.; Montero-Hidalgo, Antonio J.; Gómez-Gómez, E.; Sánchez-Sánchez, Rafael; Requena-Tapia, M.J.; Castaño, Justo P.; Gahete Ortiz, Manuel D.; Luque, Raúl M. (MDPI, 2020)Certain components of the somatostatin-system play relevant roles in Prostate Cancer (PCa), whose most aggressive phenotype (Castration-Resistant-PCa (CRPC)) remains lethal nowadays. However, neuronostatin and the G ...