Listar por autor "925244b5-371b-47a0-92da-22b379853aea"

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    • Dietary Mg Supplementation Decreases Oxidative Stress, Inflammation, and Vascular Dysfunction in an Experimental Model of Metabolic Syndrome with Renal Failure 

      López-Baltanás, Rodrigo; Rodríguez-Ortiz, Maria E.; Díaz Tocados, Juan Manuel; Martínez-Moreno, Julio M.; Membrives, Cristina; Rodelo Haad, Cristian Roberto; Pendón-Ruiz de Mier, María V.; Pendón-Ruiz de Mier, María V.; Rodríguez, Mariano; Canalejo, Antonio; Almadén Peña, Yolanda; Muñoz-Castañeda, Juan R. (MDPI, 2023)
      whether a dietary Mg supplementation might attenuate vascular dysfunction through the modulation of oxidative stress and inflammation in concurrent MetS and CKD. Methods: A rat model of MetS (Zucker strain) with CKD (5/6 ...

    • Procaine Inhibits Osteo/Odontogenesis through Wnt/β-Catenin Inactivation 

      Herencia, Carmen; Díaz Tocados, Juan Manuel; Jurado, Lidia; Montes de Oca, Addy; Rodríguez-Ortiz, Maria E.; Martín-Alonso, Carmen; Martínez-Moreno, Julio M.; Vergara, Noemi; Rodríguez, Mariano; Almadén Peña, Yolanda; Muñoz-Castañeda, Juan R. (Public Library of Science, 2016)
      Introduction Periodontitis is a complex pathology characterized by the loss of alveolar bone. The causes and the mechanisms that promote this bone resorption still remain unknown. The knowledge of the critical regulators ...

    • Study of the alterations of mineral metabolism and bone disorders associated with chronic kidney disease 

      Díaz Tocados, Juan Manuel (Universidad de Córdoba, UCOPress, 2019)
      Chronic Kidney Disease (CKD) affects million people worldwide and is a risk factor for morbidity and mortality. CKD patients have poor bone mineral density due to mineral metabolism imbalance and secondary hyperparathyroidism ...

    • TGF-β Prevents Phosphate-Induced Osteogenesis through Inhibition of BMP and Wnt/β-Catenin Pathways 

      Guerrero Pavón, Fátima; Herencia, Carmen; Almadén Peña, Yolanda; Martínez-Moreno, Julio M.; Montes de Oca, Addy; Rodríguez-Ortiz, Maria E.; Díaz Tocados, Juan Manuel; Florio, Mónica; López, Ignacio; Richards, William G.; Rodríguez Portillo, Mariano; Aguilera Tejero, Escolástico; Muñoz-Castañeda, Juan R. (Public Library of Science, 2014)
      Background: Transforming growth factor-b (TGF-b) is a key cytokine during differentiation of mesenchymal stem cells (MSC) into vascular smooth muscle cells (VSMC). High phosphate induces a phenotypic transformation of ...