Listar DBCFI-Artículos, capítulos... por título

Mostrando ítems 124-143 de 185

    • Neoflavonoids as Inhibitors of HIV-1 Replication by Targeting the Tat and NF-kB Pathways 

      Olmedo, Dionisio; López-Pérez, José L.; Olmo, Esther del; Bedoya, Luis M.; Sancho, Rocío; Alcamí, José; Muñoz, Eduardo; San Feliciano, Arturo; Gupta, Mahabir P. (MDPI, 2017)
      Twenty-eight neoflavonoids have been prepared and evaluated in vitro against HIV-1. Antiviral activity was assessed on MT-2 cells infected with viral clones carrying the luciferase reporter gene. Inhibition of HIV ...

    • Neuroprotective effect of S-allyl cysteine on an experimental model of multiple sclerosis: Antioxidant effects 

      Escribano, Begoña M.; Agüera Carmona, Eduardo; Aguilar-Luque, Macarena; Luque, Evelio; Feijóo, Montserrat; Latorre, Manuel; Giraldo, Ana I.; Galván-Jurado, A.; Caballero-Villarraso, Javier; García-Maceira, Fé I.; Santamaría, Abel; Túnez, Isaac (Elsevier, 2018)
      S-allyl cysteine (SAC), has shown itself to performance important activity as a neuroprotective agent. This action is prompted by antioxidative activity. The aim of this study was to evaluate the neuroprotective effect of ...

    • Neuroprotective Effects of Betulinic Acid Hydroxamate in Intraventricular Hemorrhage-Induced Brain Damage in Immature Rats 

      Muñoz, Eduardo; Martínez-Orgado, José; Del Pozo, Aarón; Silva, Laura; Romero, Ángela; De Hoz-Rivera, María; Villa, María; Martínez-Vega, María; Prados, María E.; Muñoz, Eduardo; Martínez-Orgado, José (MDPI, 2022)
      Intraventricular hemorrhage (IVH) is an important cause of long-term disability in extremely preterm infants, with no current treatment. We aimed to study in an IVH model in immature rats the neuroprotective effect of ...

    • Non-Coding RNAs in Kidney Diseases: The Long and Short of Them 

      Moreno, Juan Antonio; Hamza, Eya; Guerrero-Hue, Melania; Rayego-Mateos, Sandra; García-Caballero, Cristina; Vallejo-Mudarra, Mercedes; Metzinger, Laurent; Metzinger-Le Meuth, Valérie (MDPI, 2021)
      Recent progress in genomic research has highlighted the genome to be much more transcribed than expected. The formerly so-called junk DNA encodes a miscellaneous group of largely unknown RNA transcripts, which contain the ...

    • Nutritional, hormonal, and depot-dependent regulation of the expression of the small GTPase Rab18 in rodent adipose tissue 

      Pulido, Marina R.; Rabanal Ruiz, Yoana; Almabouada, Farid; Díaz-Ruiz, Alberto; Burrel, María A; Vázquez, María J.; Castaño, Justo P.; Kineman, Rhonda D.; Luque, Raúl M.; Diéguez, Carlos; Vázquez-Martínez, Rafael; Malagón, María M. (Society for Endocrinology, 2013)
      There is increasing evidence that proteins associated with lipid droplets (LDs) play a key role in the coordination of lipid storage and mobilization in adipocytes. The small GTPase, RAB18, has been recently identified as ...

    • Objective Assessment of Equine Locomotor Symmetry Using an Inertial Sensor System and Artificial Intelligence: A Comparative Study 

      Calle González, Natalie; Lo Feudo, Chiara Maria; Ferrucci, Francesco; Requena, F.; Stucchi, Luca; Muñoz, Ana (MDPI, 2024)
      In horses, quantitative assessment of gait parameters, as with the use of inertial measurement units (IMUs) systems, might help in the decision-making process. However, it requires financial investment, is time-consuming, ...

    • Odd- and Branched-Chain Fatty Acids in Lamb Meat as Potential Indicators of Fattening Diet Characteristics 

      Gómez-Cortés, Pilar; Requena Domenech, Francisco; Correro Rueda, Marta; Fuente, Miguel Ángel de la; Schiavone, Achille; Martínez Marín, Andrés L. (MDPI, 2021)
      There is a growing interest of researchers in meat authentication in terms of geographical and dietary background of animals, and several analytical methods have been proposed for the purpose of investigating this. We ...

    • Olive Oil and the Hallmarks of Aging 

      Fernández del Río, Lucía; Gutiérrez-Casado, Elena; Varela-López, Alfonso; Villalba, José Manuel (MDPI, 2016)
      Aging is a multifactorial and tissue-specific process involving diverse alterations regardedas the “hallmarks of aging”, which include genomic instability, telomere attrition, epigenetic alterations, loss of proteostasis, ...

    • Oncogenic Role of Secreted Engrailed Homeobox 2 (EN2) in Prostate Cancer 

      Gómez-Gómez, E.; Jiménez-Vacas, J.M.; Pedraza-Arévalo, Sergio; López-López, F.; Herrero-Aguayo, V.; Hormaechea Agulla, Daniel; Valero-Rosa, J.; Ibáñez-Costa, Alejandro; León González, A.J.; Sánchez-Sánchez, Rafael; Gónzalez Serrano, T.; Requena-Tapia, M.J.; Castaño, Justo P.; Carrasco-Valiente, J.; Gahete Ortiz, Manuel D.; Luque, Raúl M. (MDPI, 2019)
      Engrailed variant-2 (EN2) has been suggested as a potential diagnostic biomarker; however, its presence and functional role in prostate cancer (PCa) cells is still controversial or unknown. Here, we analyzed 1) the ...

    • Ovarian stimulation with FSH reduces phosphorylation of gonadotrope progesterone receptor and LH secretion in the rat 

      Gordon, Ana; Garrido-Gracia, José C.; Millán, Yolanda; Martín de las Mulas González-Albo, Juana; Sánchez Criado, J.E.; Aguilar, Rafaela; Guil-Luna, Silvia (Society for Reproduction and Fertility, 2009)
      Administration of human FSH(hFSH) to cyclic rats during the dioestrous phase attenuates progesterone receptor (PR)-dependent events of the preovulatory LH surge in pro-oestrus. The increased bioactivity of the putative ...

    • Parámetros cefálicos radiográficos de la oveja merina segureña y su aplicación racial 

      Vivo-Rodríguez, R.; Miró Rodríguez, F.; Rodríguez, V.; Agüera Carmona, Sergio (Universidad de Córdoba, Servicio de Publicaciones, 1988)
      Thirty-four ewes (2-3 years old) of the Merina and Segureña breeds, have been used. Lateral and ventrodorsal radiographies have been realized, obtaining data corresponding to eight parameters such as the craniumfacial angle ...

    • Parámetros fisiológicos del estrés en el toro de lidia 

      Gómez-Arias, P.; Agüera, Estrella I.; Camacho, Rocío; Camacho, J.; Requena Domenech, Francisco (RACVAO, 2019)

    • Pathogenic Pathways and Therapeutic Approaches Targeting Inflammation in Diabetic Nephropathy 

      Rayego-Mateos, Sandra; Morgado-Pascual, José Luis; Opazo-Ríos, Lucas; Guerrero-Hue, Melania; García-Caballero, Cristina; Vázquez-Carballo, Cristina; Mas, Sebastián; Sanz, Ana Belén; Herencia, Carmen; Mezzano, Sergio; Gómez-Guerrero, Carmen; Moreno, Juan Antonio; Egido, Jesús (MDPI, 2020)
      Diabetic nephropathy (DN) is associated with an increased morbidity and mortality, resulting in elevated cost for public health systems. DN is the main cause of chronic kidney disease (CKD) and its incidence increases the ...

    • Peptides derived from the extracellular domain of the somatostatin receptor splicing variant 1 SST5TMD4 increase malignancy in multiple cancer cell types 

      Río Moreno, Mercedes del; Alors-Pérez, Emilia; Borges de Souza, Patricia; Prados González, Mª Eugenia; Castaño, Justo P.; Luque, Raúl M.; Gahete Ortiz, Manuel D. (Elsevier, 2019)
      Extracellular fragments derived from plasma membrane receptors can play relevant roles in the development/progression of tumor pathologies, thereby offering novel diagnostic or therapeutic opportunities. The truncated ...

    • Preclinical Characterization of Pharmacologic NAD+Boosting as a Promising Therapeutic Approach inRheumatoid Arthritis 

      Pérez Sánchez, Carlos; Escudero Contreras, Alejandro; Cerdó, Tomás; Sánchez-Mendoza, Luz Marina; Llamas Urbano, Adrián; Arias de la Rosa, Iván; Pérez Rodríguez, Miguel; Muñoz-Barrera, Laura; Ábalos-Aguilera, María del Carmen; Barbarroja, Nuria; Calvo Gutiérrez, Jerusalém; Ortega Castro, María Rafaela; Ruiz-Vilchez, Desirée; Moreno, Juan Antonio; Burón, Isabel; González Reyes, José Antonio; López-Pedrera, Ch.; Villalba, José Manuel (Wiley, 2023)
      Objective: We analyzed NAD+ metabolism in patients with rheumatoid arthritis (RA), its association with disease activity and clinical outcomes of RA, and the therapeutic potential of pharmacologic NAD+ boosting. Methods: ...

    • Prevención de la coccidiosis de los corderos lactantes con vitamina A y Nitrofurazolidona (NFZ) 

      Vera y Vega, A.; Aparicio Ruiz, F.; Vivo-Rodríguez, R. (Universidad de Córdoba, Servicio de Publicaciones, 1979)
      Nitrofurazolidone (N. F. Z.) at 2 g/l for drinking water in addition to 20 g/Kg in starter feed associated with intrarnuscúlar dosification of vitamin A at 30 or 100 U. I./kg live weight proved to be effective in prevention ...

    • Progesterone receptor isoform A may regulate the effects of neoadjuvant aglepristone in canine mammary carcinoma 

      Guil-Luna, Silvia; Stenvang, Jan; Brünner, Nils; De Andrés, Francisco Javier; Sánchez Céspedes, Raquel; Millán, Yolanda; Martín de las Mulas González-Albo, Juana (BioMed Central, 2014)
      Background: Progesterone receptors play a key role in the development of canine mammary tumours, and recent research has focussed on their possible value as therapeutic targets using antiprogestins. Cloning and sequencing of ...

    • Promotion of pregnant merino Ewes’ Welfare with the introduction of a drought- and high-temperature-resistant cereal into their diet: analysis of tritordeum meadow 

      Agüera, Estrella I.; Requena, L.; García-Moreno García, María de los Baños; Pérez-Priego, Manuel Adolfo; Requena, F. (MDPI, 2023)
      Tritordeum is a new cereal resistant to drought and high temperatures, and it is a very healthy crop. The aim of this study was to compare two different diets (tritordeum meadow vs. oat meadow) for grazing pregnant ewes ...

    • Protective Role of Nrf2 in Renal Disease 

      Guerrero-Hue, Melania; Rayego-Mateos, Sandra; Vázquez-Carballo, Cristina; Palomino-Antolín, Alejandra; García-Caballero, Cristina; Opazo-Ríos, Lucas; Morgado-Pascual, José Luis; Herencia, Carmen; Mas, Sebastián; Ortiz, Alberto; Rubio-Navarro, Alfonso; Egea, Javier; Villalba, José Manuel; Egido, J.; Moreno, Juan Antonio (MDPI, 2020)
      Chronic kidney disease (CKD) is one of the fastest-growing causes of death and is predicted to become by 2040 the fifth global cause of death. CKD is characterized by increased oxidative stress and chronic inflammation. ...

    • Proteomic profiling of adipose tissue from Zmpste24(-/-) Mice, a model of Lipodystrophy and premature aging, reveals major changes in mitochondrial function and vimentin processing 

      Peinado, Juan R.; Moral Quirós, Pedro; Pulido, Marina R.; Mariño García, Guillermo; Martínez-Chantar, M.L.; Vázquez Martínez, Rafael; Pérez Freije, José María; López Ontín, Carlos; Malagón, María M. (Science Direct, 2011)
      Lipodystrophy is a major disease involving severe alterations of adipose tissue distribution and metabolism. Mutations in genes encoding the nuclear envelope protein lamin A or its processing enzyme, the metalloproteinase ...