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Transcriptomic Coordination in the Human Metabolic Network Reveals Links between n-3 Fat Intake, Adipose Tissue Gene Expression and Metabolic Health
(Public Library Of Science (PLOS), 2011)
Understanding the molecular link between diet and health is a key goal in nutritional systems biology. As an alternative to
pathway analysis, we have developed a joint multivariate and network-based approach to analysis ...
Effects of rs7903146 Variation in the Tcf7l2 Gene in the Lipid Metabolism of Three Different Populations
(Public Library Of Science (PLOS), 2012)
Background: TCF7L2 rs7903146 is an important genetic factor predicting type 2 diabetes (T2DM) which has also been linked
to higher cardiovascular risk. To date, there is little information about the additional impact of ...
Glucokinase Regulatory Protein Genetic Variant Interacts with Omega-3 PUFA to Influence Insulin Resistance and Inflammation in Metabolic Syndrome
(Public Library Of Science (PLOS), 2011)
Glucokinase Regulatory Protein (GCKR) plays a central role regulating both hepatic triglyceride and glucose metabolism.
Fatty acids are key metabolic regulators, which interact with genetic factors and influence glucose ...
Aceite de oliva y prevención cardiovascular: más que una grasa
(Instituto de Estudio Jiennenses, 2007)
Proteome from patients with metabolic syndrome is regulated by quantity and quality of dietary lipids
(BioMed Central, 2015)
Background: Metabolic syndrome is a multi-component disorder associated to a high risk of cardiovascular disease.
Its etiology is the result of a complex interaction between genetic and environmental factors, including ...
Influence of Obesity and Metabolic Disease on Carotid Atherosclerosis in Patients with Coronary Artery Disease (CordioPrev Study)
(Public Library of Science, 2016)
Background
Recent data suggest that the presence of associated metabolic abnormalities may be
important modifiers of the association of obesity with a poorer prognosis in coronary heart
disease. We determined the influence ...
The Role of Emotional Regulation and Affective Balance on Health Perception in Cardiovascular Disease Patients According to Sex Differences
(MDPI, 2020)
One of the challenges of aging is the increase of people with chronic diseases, such as cardiovascular disease (CVD). Men and women experience the disease differently. Therefore, it has an impact on how CVD is treated and ...
Hepatic insulin resistance both in prediabetic and diabetic patients determines postprandial lipoprotein metabolism: from the CORDIOPREV study
(BioMed Central, 2016)
Background/aims: Previous evidences have shown the presence of a prolonged and exaggerated postprandial
response in type 2 diabetes mellitus (T2DM) and its relation with an increase of cardiovascular risk. However, ...
A plasma fatty acid profile associated to type 2 diabetes development: from the CORDIOPREV study
(Springer, 2021)
Purpose: The prevalence of type 2 diabetes mellitus (T2DM) is increasing worldwide. For this reason, it is essential to identify biomarkers for the early detection of T2DM risk and/or for a better prognosis of T2DM. We ...
Evolution of Metabolic Phenotypes of Obesity in Coronary Patients after 5 Years of Dietary Intervention: From the CORDIOPREV Study
(MDPI, 2021)
Background: Obesity phenotypes with different metabolic status have been described previously. We analyzed metabolic phenotypes in obese coronary patients during a 5-year follow-up, and examined the factors influencing ...