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The Sigma Class Glutathione Transferase from the Liver Fluke Fasciola hepatica
(Public Library Of Science (PLOS), 2012)
Background: Liver fluke infection of livestock causes economic losses of over US$ 3 billion worldwide per annum. The
disease is increasing in livestock worldwide and is a re-emerging human disease. There are currently no ...
Caracterización de macrófagos peritoneales de ovejas en fases tempranas de infección experimental con fasciola hepática
(Universidad de Córdoba. Departamento de Anatomía y Anatomía Patológica Comparadas, 2016)
Vaccines against helminth parasites of livestock of economic and/or public health significance (PARAVAC)
(Oficina de Transferencia de Resultados de la Investigación, 2013)
El proyecto PARAVAC está financiado por el VII Programa Marco con una aportación de la Comisión Europea de unos 9 millones de euros. El principal objetivo de este proyecto es el desarrollo y comercialización de vacunas ...
Distribution of Foxp3+ T cells in the liver and hepatic lymph nodes of goats and sheep experimentally infected with Fasciola hepatica
(Elsevier, 2016)
Foxp3 regulatory T cells (Tregs) are now considered to play a key role in modulation of immune responses during parasitic helminth infections. Immunomodulation is a key factor in Fasciola hepatica infection; however, the ...
A Partially Protective Vaccine for Fasciola hepatica Induced Degeneration of Adult Flukes Associated to a Severe Granulomatous Reaction in Sheep
(MDPI, 2021)
Fasciolosis is an important economic disease of livestock. There is a global interest in the development of protective vaccines since current anthelmintic therapy is no longer sustainable. A better knowledge of the ...
Fasciola hepatica primoinfections and reinfections in sheep drive distinct Th1/Th2/Treg immune responses in liver and hepatic lymph node at early and late stages
(Springer, 2023)
The expression of proinflammatory (IL-1β, IFN-γ, TNF-α) and regulatory (IL-10, TGF-β, IL-4) cytokines, as well as the
transcription factor FoxP3, was quantified in the liver and hepatic lymph node (HLN) of sheep primoinfected ...