The homeodomain transcription factor Ste12: Connecting fungal MAPK signalling to plant pathogenicity
Autor
Rispail, Nicolás
Di Pietro, Antonio
Editor
Landes BioscienceFecha
2010Materia
Ste12Signaling
Virulence
Plant pathogen
Fungal pathogenicity
MAPK cascade
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A conserved mitogen-activated protein kinase (MAPK) cascade orthologous to
the mating/filamentation MAPK pathway in yeast is required for fungal pathogenicity
on plants. One of the key targets of this signalling pathway is the homeodomain
transcription factor Ste12. Mutational analysis of ste12 orthologues in a variety of
plant pathogenic fungi suggests that Ste12 functions as a master regulator of
invasive growth. In this mini-review we highlight recent progress in understanding the
role of Ste12 in filamentous fungi and discuss future challenges of unravelling the
mechanisms by which Ste12 controls fungal virulence downstream of the
Pathogenicity MAPK cascade