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Colecciones en esta comunidad

Envíos recientes

  • Effect of Cytomegalovirus (CMV) and Ageing on T-Bet and Eomes Expression on T-Cell Subsets 

    Hassouneh, Fakhri; López-Sejas, Nelson; Sánchez-Correa, Beatriz; Tarazona, Raquel; Solana Lara, Rafael; Pera Rojas, Alejandra; Campos Fernández, Carmen (MDPI, 2017)
    The differential impact of ageing and cytomegalovirus (CMV) latent infection on human T-cell subsets remains to some extent controversial. The purpose of this study was to analyse the expression of the transcription factors ...
  • Activation of microglia in specific hypothalamic nuclei and the cerebellum of adult rats exposed to neonatal overnutrition 

    Tapia-González, S.; García-Segura, L.M.; Tena-Sempere, Manuel; Frago, L.M.; Castellano, J.M.; Fuente-Martín, E.; García-Cáceres, C.; Argente, J.; Chowen, J.A. (Blackwell Publishing, 2011)
    Much attention has been drawn to the possible involvement of hypothalamic inflammation in the pathogenesis of metabolic disorders, especially in response to a high-fat diet. Microglia, the macrophages of the central nervous ...
  • Neoflavonoids as Inhibitors of HIV-1 Replication by Targeting the Tat and NF-kB Pathways 

    Olmedo, Dionisio; López-Pérez, José L.; Olmo, Esther del; Bedoya, Luis M.; Sancho, Rocío; Alcamí, José; Muñoz, Eduardo; San Feliciano, Arturo; Gupta, Mahabir P. (MDPI, 2017)
    Twenty-eight neoflavonoids have been prepared and evaluated in vitro against HIV-1. Antiviral activity was assessed on MT-2 cells infected with viral clones carrying the luciferase reporter gene. Inhibition of HIV ...
  • Olive Oil and the Hallmarks of Aging 

    Fernández del Río, Lucía; Gutiérrez-Casado, Elena; Varela-López, Alfonso; Villalba, José Manuel (MDPI, 2016)
    Aging is a multifactorial and tissue-specific process involving diverse alterations regarded as the “hallmarks of aging”, which include genomic instability, telomere attrition, epigenetic alterations, loss of proteostasis, ...
  • 3-Phenylcoumarins as Inhibitors of HIV-1 Replication 

    Olmedo, Dionisio; Sancho, Rocío; Bedoya, Luis M.; López-Pérez, José L.; Olmo, Esther del; Muñoz, Eduardo; Alcamí, José; Gupta, Mahabir P.; San Feliciano, Arturo (MDPI, 2012)
    We have synthesized fourteen 3-phenylcoumarin derivatives and evaluated their anti-HIV activity. Antiviral activity was assessed on MT-2 cells infected with viral clones carrying the luciferase gene as reporter. Inhibition ...

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