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Elaboración de modelos anatómicos mediante técnicas de plastinación como alternativa al uso de animales en docencia y como recurso esencial en el proceso de enseñanza-aprendizaje
(UCOPress, 2019)
La implantación del principio de las 3Rs (Reducción, Refinamiento y Reemplazo), descritas por Russell y Burch en 1959, fue el punto de partida de numerosos cambios en la utilización de los animales, tanto en el ámbito de ...
Proteomic profile of the effects of low-dose bisphenol A on zebrafish ovaries
(Elsevier, 2021)
Human exposure to bisphenol-A (BPA) is largely unavoidable because BPA is an environmental contaminant found in soil, water, food and indoor dust. The safety of authorized BPA amounts in consumer products is under question ...
Analysis of Indirect Biomarkers of Effect after Exposure to Low Doses of Bisphenol A in a Study of Successive Generations of Mice
(MDPI, 2022)
Bisphenol A (BPA) is considered as being an emerging pollutant, to which both animal and human populations are continuously and inadvertently exposed. The identification of indirect biomarkers of effect could be a key ...
Evaluation of the Toxicity of Bisphenol A in Reproduction and Its Effect on Fertility and Embryonic Development in the Zebrafish (Danio rerio)
(MDPI, 2022)
Bisphenol A (BPA) is a chemical substance commonly used in the manufacture of plastic products. Its inhalation or ingestion from particles in suspension, water, and/or polluted foods can trigger toxic effects related to ...
Immunohistochemical expression of aromatase cyp19a1a and cyp19a1b in the ovary and brain of zebrafish (Danio rerio) exposed to different concentrations of bisphenol A
(Elsevier, 2021)
Bisphenol A (BPA) is used to produce plastic and plastic derived products in multitude of daily utensils, being one of the industrial compounds most widely used. This endocrine disrupting chemical (EDCs) is a well-known ...
Assessment of the effects of bisphenol-A as a disruptor on ionic regulation in Danio rerio zebrafish through a study of their chloride and prolactin cells
(Institute of Oceanography and Fisheries, 2017)
Bisphenol A (BPA) is one of the chemicals produced in the largest volume in the world. It is
commonly used as a component of plastics and food containers and can act as a xenoestrogen in
humans. In view of the risk of ...
Analyses of anaesthesia with ketamine combined with different sedatives in rats
(Czech Academy of Agricultural Sciences, 2015)
The goal of this study was to establish an easy-to-perform, reliable, and safe protocol for intraperitoneal injection anaesthesia in rats, as well as an easy method to assess anaesthesia depth under routine clinical ...
Evaluation of toxicological endpoints in female zebrafish after bisphenol A exposure
(Elsevier, 2018)
Given the importance of bisphenol A (BPA) as a xenoestrogen and its potential effects on human and animal, we evaluated BPA exposure's short-term effects on follicular development, yolk protein vitellogenin (VTG) production ...