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Progesterone receptor isoform A may regulate the effects of neoadjuvant aglepristone in canine mammary carcinoma
(BioMed Central, 2014)
Background: Progesterone receptors play a key role in the development of canine mammary tumours, and recent
research has focussed on their possible value as therapeutic targets using antiprogestins. Cloning and sequencing
of ...
Progesterone Receptor Isoform Analysis by Quantitative Real-Time Polymerase Chain Reaction in Formalin-Fixed, Paraffin-Embedded Canine Mammary Dysplasias and Tumors
(Sage, 2014)
Cloning and sequencing of the progesterone receptor gene in dogs have revealed 2 isoforms, A and B, transcribed from a single gene. Distribution of isoforms A and B in canine mammary lesions has hitherto been investigated ...
Aglepristone decreases proliferation in progesterone receptor-positive canine mammary carcinomas
(Wiley, 2011)
Progesterone receptor (PR) antagonist aglepristone (RU534) has been used successfully for pregnancy termination and therapy of pyometra, vaginal tumors, and mammary hyperplasia in bitches and queens. All of these conditions ...