Listar por autor "bac466af-900c-4b9b-bc77-88ade0457e34"
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A specific N-terminal extension of the 8 kDa domain is required for DNA end-bridging by human Polµ and Polλ
Martín, M.J.; García-Ortiz, M.V.; Gómez-Bedoya, Ana; Esteban, Verónica; Guerra, Susana; Blanco, Luis (Oxford University Press, 2013)Human DNA polymerases mu (Polµ) and lambda (Polλ) are X family members involved in the repair of double-strand breaks in DNA during non-homologous end joining. Crucial abilities of these enzymes include bridging of the two ... -
Ribonucleotides and manganese ions improve non-homologous end joining by human Polμ
Martín, M.J.; García-Ortiz, M.V.; Esteban, Verónica; Blanco, Luis (Oxford University Press, 2013)Human DNA polymerase mu (Polμ), a family X member involved in DNA repair, has both template-directed and terminal transferase (template-independent) activities. In addition to their ability to incorporate untemplated ...