• Activation of microglia in specific hypothalamic nuclei and the cerebellum of adult rats exposed to neonatal overnutrition 

      Tapia-González, S.; García-Segura, L.M.; Tena-Sempere, Manuel; Frago, L.M.; Castellano, J.M.; Fuente-Martín, E.; García-Cáceres, C.; Argente, J.; Chowen, J.A. (Blackwell Publishing, 2011)
      Much attention has been drawn to the possible involvement of hypothalamic inflammation in the pathogenesis of metabolic disorders, especially in response to a high-fat diet. Microglia, the macrophages of the central nervous ...
    • Alternative Foods in Cardio-Healthy Dietary Models That Improve Postprandial Lipemia and Insulinemia in Obese People 

      Muñoz-Pérez, Diana María; González-Correa, Clara Helena; Astudillo-Muñoz, Elcy Yaned; Porras-Hurtado, Gloria Liliana; Sánchez-Giraldo, Maite; López-Miranda, José; Camargo García, A.; Rangel Zúñiga, Oriol Alberto (MDPI, 2021)
      Obesity is one of the major health problems worldwide. Following healthy dietary patterns can be difficult in some countries due to the lack of availability of certain foods; thus, alternative foods are needed. Our aim was ...
    • An Approach to Early Detection of Metabolic Syndrome through Non-Invasive Methods in Obese Children 

      Molina Luque, Rafael; Ulloa, Natalia; Gleisner, Andrea; Zilic, Martin; Romero Saldaña, Manuel; Molina Recio, Guillermo (MDPI, 2020)
      Background: Metabolic Syndrome (MetS) has a high prevalence in children, and its presence increases in those with a high BMI. This fact confirms the need for early detection to avoid the development of other comorbidities. ...
    • Aquaporin-11 Contributes to TGF-β1-Induced Endoplasmic Reticulum Stress in Human Visceral Adipocytes: Role in Obesity-Associated Inflammation 

      Frühbeck, Gema; Balaguer, Inmaculada; Méndez-Giménez, Leire; Valentí, Víctor; Becerril, Sara; Catalán, Victoria; Gómez-Ambrosi, Javier; Silva, Camilo; Salvador, Javier; Calamita, Giuseppe; Malagón, María M.; Rodríguez, Amaia (MDPI, 2020)
      Aquaporin-11 (AQP11) is expressed in human adipocytes, but its functional role remains unknown. Since AQP11 is an endoplasmic reticulum (ER)-resident protein that transports water, glycerol, and hydrogen peroxide (H2O2), ...
    • Caracterización de las conexiones intracelulares que definen la expansión disfuncional del tejido adiposo en obesidad 

      López Alcalá, Jaime David (Universidad de Córdoba, UCOPress, 2024)
      El tejido adiposo desempeña un papel esencial en la gestión de las reservas energéticas del organismo. Los adipocitos son las células más abundantes del tejido adiposo y constituyen su unidad funcional. Están especializados ...
    • Changes in Physical Activity Patterns from Childhood to Adolescence: Genobox Longitudinal Study 

      Llorente Cantarero, Francisco Jesús; Aguilar-Gómez, Francisco Javier; Anguita-Ruiz, Augusto; Rupérez, Azahara I.; Vázquez-Cobela, Rocío; Flores Rojas, Katherine Ubina; Aguilera, Concepción M.; González-Gil, Esther M.; Gil Campos, Mercedes; Bueno, Gloria; Leis, Rosaura (MDPI, 2020)
      Longitudinal changes of physical activity (PA) from childhood into adolescence have not been accurately described yet for the Spanish population. The aim of this study is to evaluate the changes of PA, assessed by accelerometry ...
    • Clinical Effectiveness and Safety of Once-Weekly GLP-1 Receptor Agonist Dulaglutide as Add-On to Metformin or Metformin Plus Insulin Secretagogues in Obesity and Type 2 Diabetes 

      Mirabelli, María; Chiefari, Eusebio; Tocci, Vera; Caroleo, Patrizia; Giuliano, Stefania; Greco, Emanuela; Luque, Raúl M.; Puccio, Luigi; Foti, Daniela Patrizia; Aversa, Antonio; Brunetti, Antonio (MDPI, 2021)
      Aims and methods: The aim of this monocentric retrospective observational study was to evaluate the 18-month safety and effectiveness of GLP-1 receptor agonist (GLP-1 RA) dulaglutide (DU) 1.5 mg/once weekly as an add-on ...
    • Common Variants in 22 Genes Regulate Response to Metformin Intervention in Children with Obesity: A Pharmacogenetic Study of a Randomized Controlled Trial 

      Anguita-Ruiz, Augusto; Pastor-Villaescusa, Belén; Leis, Rosaura; Bueno, Gloria; Hoyos, Raúl; Vázquez-Cobela, Rocío; Latorre Millán, Miriam; Cañete Estrada, Ramón; Caballero-Villarraso, Javier; Gil, Ángel; Aguilera, Concepción M. (MDPI, 2019)
      Metformin is a first-line oral antidiabetic agent that has shown additional effects in treating obesity and metabolic syndrome. Inter-individual variability in metformin response could be partially explained by the genetic ...
    • Economía de la Alimentación 

      Ortiz Jurado, Andrea; Molina Bielza, Elena (Universidad de Córdoba, Facultad de Derecho y CC. EE. y Empresariales, 2019)
      La alimentación ha evolucionado desde considerarse simplemente un elemento indispensable para satisfacer nuestras necesidades fisiológicas hasta convertirse en un componente a través del cual obtenemos placer y disfrute. ...
    • Effect of 8-Week Consumption of a Dietary Pattern Based on Fruit, Avocado, Whole Grains, and Trout on Postprandial Inflammatory and Oxidative Stress Gene Expression in Obese People 

      López-Miranda, José; Muñoz-Pérez, Diana María; González-Correa, Clara Helena; Astudillo-Muñoz, Elcy Yaned; Sánchez-Giraldo, Maite; Carmona-Hernández, Juan Carlos; López-Miranda, José; Camargo García, A.; Rangel Zúñiga, Oriol Alberto (MDPI, 2023)
      Overweight and obesity constitute a major global public health problem. Healthy dietary patterns induce changes at the molecular level. Currently, there are no studies evaluating the effect of a diet based on fruit, avocado, ...
    • Effectiveness of Exercise in Patients with Overweight or Obesity Suffering from Knee Osteoarthritis: A Systematic Review and Meta-Analysis 

      Jurado-Castro, José Manuel; Muñoz-López, Mariano; Sánchez-Toledo, Agustín; Ranchal-Sánchez, Antonio (MDPI, 2022)
      The main purpose of this study was to review the evidence about the effectiveness of exercise in patients with overweight or obesity suffering from knee osteoarthritis. Methods: Randomized clinical trials (RCTs) published ...
    • Effectiveness of multicomponent interventions and physical activity in the workplace to reduce obesity: a systematic review and meta-analysis 

      Jiménez Mérida, Mª del Rocío; Vaquero Abellán, Manuel; Alcaide-Leyva, José M.; Cantón-Habas, Vanesa; Raya-Cano, Elena; Romero Saldaña, Manuel (MDPI, 2023)
      Background: Overweight and obesity are public health problems that affects the workplace. This paper aims to analyse the effectiveness of workplace health promotion interventions in reducing Body Mass Index (BMI); Methods: ...
    • Epidemiologic Behavior of Obesity in the Maracaibo City Metabolic Syndrome Prevalence Study 

      López-Miranda, José; Bermúdez Pirela, Valmore José; Pacheco, Maikol; Rojas, Joselyn; Córdova, Evelyn; Velázquez, Rossibel; Carrillo, Daniela; Parra, María G.; Toledo, Alexandra; Añez, Roberto; Fonseca, Eneida; París Marcano, Rafael; Cano, Clímaco; López-Miranda, José (Public Libray of Science (PLOS), 2012)
      Introduction: Obesity is a worldwide public health issue. Since the epidemiological behaviour of this disease is not well established in our country, the purpose of this study was to determinate its prevalence in the ...
    • Equation Córdoba: A Simplified Method for Estimation of Body Fat (ECORE-BF) 

      Molina Luque, Rafael; Romero Saldaña, Manuel; Álvarez-Fernández, Carlos; Bennasar-Veny, Miquel; Álvarez-López, Álvaro; Molina Recio, Guillermo (MDPI, 2019)
      Background: Many methods for measuring body fat have been developed, but applications in clinical settings are limited. For this reason, researchers have tried to identify different formulas for its estimation but most of ...
    • Estilos de vida y estado de salud cardiovascular de una población escolar 

      Vaquero Álvarez, Manuel (Universidad de Córdoba, 2018)
      La detección precoz y el tratamiento temprano son fundamentales para las personas con enfermedad cardiovascular o con alto riesgo cardiovascular. Objetivos. Conocer el estado de salud cardiovascular y estilos de vida de ...
    • Evaluation of the combined glucose-insulin and intravenous glucose tolerance tests for insulin dysregulation diagnosis in donkeys 

      Mendoza García, Francisco Javier; Mejía-Moreira, Sebastián; Buchanan, Ben R.; Toribio, Ramiro E.; Pérez-Ecija, Alejandro (Wiley, 2021)
      Background. Insulin dysregulation (ID) and donkey metabolic syndrome (DMS) are common in this species. Contrary to horses, diagnostic guidelines compiling insulin cut-offs values and dynamic testing interpretations have ...
    • Flavonoid Phloretin Inhibits Adipogenesis and Increases OPG Expression in Adipocytes Derived from Human Bone-Marrow Mesenchymal Stromal-Cells 

      Casado‐Díaz, Antonio; Rodríguez Ramos, Ángel; Torrecillas‐Baena, Bárbara; Dorado, G.; Quesada Gómez, José Manuel; Gálvez-Moreno, M. Ángeles (MDPI, 2021)
      Phloretin (a flavonoid abundant in apple), has antioxidant, anti-inflammatory, and glucose-transporter inhibitory properties. Thus, it has interesting pharmacological and nutraceutical potential. Bone-marrow mesenchymal ...
    • Genome-Wide Expression in Visceral Adipose Tissue from Obese Prepubertal Children 

      Aguilera García, Concepción; Gómez-Llorente, Carolina; Tofé, Inés; Gil Campos, Mercedes; Cañete Estrada, Ramón; Gil, Ángel (MDPI, 2015)
      Characterization of the genes expressed in adipose tissue (AT) is key to understanding the pathogenesis of obesity and to developing treatments for this condition. Our objective was to compare the gene expression in visceral ...
    • Google Trends on Obesity, Smoking and Alcoholism: Global and Country-Specific Interest 

      Fabbian, Fabio; Rodríguez Muñoz, Pedro Manuel; López-Carrasco, Juan de la Cruz; Cappadona, Rosaria; Rodríguez Borrego, M.A.; López Soto, Pablo Jesús (MDPI, 2021)
      Unhealthy habits or lifestyles, such as obesity, smoking, and alcohol consumption, are involved in the development of non-communicable diseases. The aim of this study was to analyze different communities’ interest in seeking ...
    • Ibero–American Consensus on Low- and No-Calorie Sweeteners: Safety, Nutritional Aspects and Benefits in Food and Beverages 

      Serra-Majem, Lluis; Raposo, Antonio; Aranceta-Bartrina, Javier; Varela-Moreiras, Gregorio; Logue, Caomhan; Laviada, Hugo; Socolovsky, Susana; Pérez-Rodrigo, Carmen; Aldrete-Velasco, Jorge Antonio; Meneses Sierra, Eduardo; López-García, Rebeca; Ortiz-Andrelluchi, Adriana; Gómez-Candela, Carmen; Abreu, Rodrigo; Alexanderson, Erick; Álvarez-Álvarez, Rolando Joel; Álvarez Falcón, Ana Luisa; Anadón, Arturo; Bellisle, France; Beristain-Navarrete, Ina Alejandra; Blasco Redondo, Raquel; Bochicchio, Tommaso; Camolas, José; Cardina, Fernando G.; Carocho, Márcio; Costa, Maria do Céu; Drewnowski, Adam; Durán, Samuel; Faundes, Víctor; Fernández-Condori, Roxana; García-Luna, Pedro P.; Garnica, Juan Carlos; González-Gross, Marcela; La Vecchia, Carlo; Leis, Rosaura; López-Sobaler, Ana María; Madero, Miguel Agustín; Marcos, Ascensión; Mariscal Ramírez, Luis Alfonso; Martyn, Danika M.; Mistura, Lorenza; Moreno Rojas, Rafael; Moreno Villares, José Manuel; Niño-Cruz, José Antonio; Oliveira, María Beatriz P.P.; Palacios Gil-Antuñano, Nieves; Pérez-Castells, Lucía; Ribas-Barba, Lourdes; Rincón Pedrero, Rodolfo; Riobó, Pilar; Rivera Medina, Juan; Tinoco de Faria, Catalina; Valdés-Ramos, Roxana; Vasco, Elsa; Wac, Sandra N.; Wakida, Guillermo; Wanden-Berghe, Carmina; Xóchihua Díaz, Luis; Zúñiga-Guajardo, Sergio; Pyrogianni, Vasiliki; Velho de Souza, Sérgio Cunha (MDPI, 2018)
      International scientific experts in food, nutrition, dietetics, endocrinology, physical activity, paediatrics, nursing, toxicology and public health met in Lisbon on 2–4 July 2017 to develop a Consensus on the use of ...