• Identification of a translatable animal model for dry eye disease using comparative analysis of tear proteins across species 

  Pérez-Perdomo, Mayelin; González-López, Ana; Ortega-Llamas, Laura; Alba-Molina, David; Blanco-Blanco, Mario; Granados Machuca, Maria del Mar; Guerrero-Moreno, Adrián; Pflugfelder, Stephen Carl; Ullmer, Christoph; Fauser, Sascha; Jiménez-Gómez, Yolanda; González Andrades, Miguel (Elsevier, 2025)

  Purpose This study aimed to assess the similarity of tear proteins between experimental animals and humans to identify the most translational animal model for dry eye disease (DED). Methods Eleven species were selected ...

• Assessment of early postoperative oxygenation after the application of a stepwise alveolar recruitment manoeuvre before anaesthesia recovery in healthy sheep 

  Navarrete Calvo, Rocío; Parra, Pablo; Morgaz, Juan; Gómez Villamandos, Rafael Jesús; Domínguez, Juan M.; Quirós Carmona, Setefilla; Medina-Bautista, Francisco; Granados Machuca, María del Mar (Elsevier, 2025)

  This study evaluated the effect of a stepwise alveolar recruitment manoeuvre (ARM) at the end of anaesthesia on arterial oxygenation and shunt fraction (F-shunt) during the early postoperative period in sheep. Twenty-four ...

• Effect of warming method on embryo quality in a simplified equine embryo vitrification system 

  Siqueira Canesin, Heloisa; Ortiz, I.; Rocha Filho, Alexandre; Mayrink Salgado, Renato; Gatto Brom de Luna, Joao; Hinrichs, Katrin (Elsevier, 2020)

  Equine embryo vitrification is still not a well-established technique in equine practice. Notably, little work has been done on the effect of the warming system on viability of vitrified embryos. Our goal was to evaluate ...

• Factors affecting intracellular calcium influx in response to calcium ionophore A23187 in equine sperm 

  Sampaio, Breno; Ortiz, I.; Resende, Helene; Felix, Matheus; Varner, Dickson; Hinrichs, Katrin (Wiley, 2021)

  Background: Exposure to the calcium ionophore A23187 may present a “universal” sperm treatment for IVF, as it bypasses capacitation pathways. However, success in utilizing A23187 is variable, especially in equine ...

• Time-lapse imaging and developmental competence of donkey eggs after ICSI: Effect of preovulatory follicular fluid during oocyte in vitro maturation 

  Flores Bragulat, Ana; Ortiz, I.; Catalán, Jaime; Dorado, Jesús; Hidalgo, Manuel; Losinno, Luis; Dordas-Perpinya, Marta; Yánez-Ortiz, Iván; Martínez-Rodero, Iris; Miro, Jordi; Gambini, Andrés (Elsevier, 2022)

  Equus members exhibit very divergent karyotype, genetic plasticity, and significant differences in their reproductive physiology. Despite the fact that somatic cell nuclear transfer and intracytoplasmic sperm injection ...

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