Show simple item record

dc.contributor.authorArenas de Larriva, Antonio P.
dc.contributor.authorLimia-Pérez, Laura
dc.contributor.authorAlcalá Díaz, Juan Francisco
dc.contributor.authorAlonso, Álvaro
dc.contributor.authorLópez-Miranda, José
dc.contributor.authorDelgado-Lista, Javier
dc.date.accessioned2020-10-22T06:31:13Z
dc.date.available2020-10-22T06:31:13Z
dc.date.issued2020
dc.identifier.urihttp://hdl.handle.net/10396/20561
dc.description.abstractSeveral studies indicate that oxidative stress might play a central role in the initiation and maintenance of cardiovascular diseases. It remains unclear whether ceruloplasmin acts as a passive marker of inflammation or as a causal mediator. To better understand the impact of ceruloplasmin blood levels on the risk of cardiovascular disease, and paying special attention to coronary heart disease, we conducted a search on the two most commonly used electronic databases (Medline via PubMed and EMBASE) to analyze current assessment using observational studies in the general adult population. Each study was quality rated using criteria developed by the US Preventive Services Task Force. Most of 18 eligible studies reviewed support a direct relationship between ceruloplasmin elevated levels and incidence of coronary heart disease. Our results highlight the importance of promoting clinical trials that determine the functions of ceruloplasmin as a mediator in the development of coronary heart disease and evaluate whether the treatment of elevated ceruloplasmin levels has a role in the prognosis or prevention of this condition.es_ES
dc.format.mimetypeapplication/pdfes_ES
dc.language.isoenges_ES
dc.publisherMDPIes_ES
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/4.0/es_ES
dc.sourceNutrients 12(10), 3219 (2020)es_ES
dc.subjectCeruloplasmines_ES
dc.subjectCoronary heart diseasees_ES
dc.subjectInflammationes_ES
dc.titleCeruloplasmin and Coronary Heart Disease-A Systematic Reviewes_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.relation.publisherversionhttp://dx.doi.org/10.3390/nu12103219es_ES
dc.rights.accessRightsinfo:eu-repo/semantics/openAccesses_ES


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record