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Unleashing the Diagnostic, Prognostic and Therapeutic Potential of the Neuronostatin/GPR107 System in Prostate Cancer

Sáez Martínez, Prudencio; Jiménez-Vacas, J.M.; León González, A.J.; Herrero-Aguayo, V.; Montero-Hidalgo, Antonio J.; Gómez-Gómez, E.; Sánchez-Sánchez, Rafael; Requena-Tapia, M.J.; Castaño, Justo P.; Gahete Ortiz, Manuel D.; Luque, Raúl M. (MDPI, 2020)

Certain components of the somatostatin-system play relevant roles in Prostate Cancer (PCa), whose most aggressive phenotype (Castration-Resistant-PCa (CRPC)) remains lethal nowadays. However, neuronostatin and the G ...

Enzima GOAT como biomarcador de diagnóstico del cáncer de próstata

Castaño, Justo P.; Luque, Raúl M.; Gahete Ortiz, Manuel D.; Hormaechea Agulla, Daniel; Requena-Tapia, M.J.; Gómez Gómez, Enrique; Carrasco, Julia; Ibáñez, Alejandro; Moreno, María del Mar; Valero, José (Oficina de Transferencia de Resultados de la Investigación, 2020)

Effectiveness of Virtual Reality on Functional Performance after Spinal Cord Injury: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Miguel-Rubio, Amaranta de; Rubio Luque, M.D.; Salazar, Alejandro; Camacho, Rocío; Lucena-Antón, David (MDPI, 2020)

A spinal cord injury (SCI) usually results in a significant limitation in the functional outcomes, implying a challenge to the performance of activities of daily living. The main aim of this study is to analyze the ...

Characterization of the DNAM-1, TIGIT and TACTILE Axis on Circulating NK, NKT-Like and T Cell Subsets in Patients with Acute Myeloid Leukemia

Valhondo, Isabel; Hassouneh, Fakhri; López-Sejas, Nelson; Pera Rojas, Alejandra; Sánchez-Correa, Beatriz; Guerrero, Beatriz; Bergua, Juan M.; Arcos, María José; Bañas, Helena; Casas-Avilés, Ignacio; Sánchez García, Joaquín; Serrano, Josefina; Martín, Carmen; Durán, Esther; Alonso, Corona; Solana, Rafael; Tarazona, Raquel (MDPI, 2020)

Background: Acute myeloid leukemia (AML) remains a major clinical challenge due to poor overall survival, which is even more dramatic in elderly patients. TIGIT, an inhibitory receptor that interacts with CD155 and CD112 ...

Los ASPECTOS INMUNOLÓGICOS de la respuesta al virus SARS-CoV-2 responsable de la enfermedad denominada COVID-19

Solana Lara, Rafael (Universidad de Córdoba, 2020)

Endothelial Dysfunction and Advanced Glycation End Products in Patients with Newly Diagnosed Versus Established Diabetes: From the CORDIOPREV Study

Cruz‐Ares, Silvia de la; Cardelo, Magdalena P.; Gutiérrez Mariscal, Francisco Miguel; Torres‑Peña, J.D.; García-Ríos, Antonio; Katsiki, Niki; Malagón, María M.; López-Miranda, José; Pérez-Martínez, Pablo; Yubero-Serrano, Elena M. (MDPI, 2020)

Endothelial dysfunction and intima-media thickness of common carotid arteries (IMT-CC) are considered subclinical markers of atherosclerotic cardiovascular disease (ASCVD). Advanced glycation end products (AGEs) are increased ...

A Meta-Analytic Approach to Predict Methane Emissions from Dairy Goats Using Milk Fatty Acid Profile

Requena Domenech, Francisco; Peña Blanco, Francisco; Agüera Buendía, Estrella; Martínez Marín, Andrés L. (MDPI, 2020)

The aim of this work was to develop an equation to predict methane yield (CH4, g/kg dry matter intake) from dairy goats using milk fatty acid (FA) profile. Data from 12 research papers (30 treatments and 223 individual ...

Aquaporin-11 Contributes to TGF-β1-Induced Endoplasmic Reticulum Stress in Human Visceral Adipocytes: Role in Obesity-Associated Inflammation

Frühbeck, Gema; Balaguer, Inmaculada; Méndez-Giménez, Leire; Valentí, Víctor; Becerril, Sara; Catalán, Victoria; Gómez-Ambrosi, Javier; Silva, Camilo; Salvador, Javier; Calamita, Giuseppe; Malagón, María M.; Rodríguez, Amaia (MDPI, 2020)

Aquaporin-11 (AQP11) is expressed in human adipocytes, but its functional role remains unknown. Since AQP11 is an endoplasmic reticulum (ER)-resident protein that transports water, glycerol, and hydrogen peroxide (H2O2), ...

Pathogenic Pathways and Therapeutic Approaches Targeting Inflammation in Diabetic Nephropathy

Rayego-Mateos, Sandra; Morgado-Pascual, José Luis; Opazo-Ríos, Lucas; Guerrero-Hue, Melania; García-Caballero, Cristina; Vázquez-Carballo, Cristina; Mas, Sebastián; Sanz, Ana Belén; Herencia, Carmen; Mezzano, Sergio; Gómez-Guerrero, Carmen; Moreno, Juan Antonio; Egido, Jesús (MDPI, 2020)

Diabetic nephropathy (DN) is associated with an increased morbidity and mortality, resulting in elevated cost for public health systems. DN is the main cause of chronic kidney disease (CKD) and its incidence increases the ...

Hematuria Is Associated with More Severe Acute Tubulointerstitial Nephritis

Esteras, Raquel; Fox, Jonathan G.; Geddes, Colin C.; Mackinnon, Bruce; Ortiz, Alberto; Moreno, Juan Antonio (MDPI, 2020)

Acute tubulointerstitial nephritis (ATIN) is a common cause of acute kidney injury. Although haematuria is a risk factor for the development of renal disease, no previous study has analyzed the significance of haematuria ...