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Metabolic Fingerprint of Acromegaly and its Potential Usefulness in Clinical Practice

Biagetti, Betina; Herance, J.R.; Ferrer, Roser; Aulinas, Anna; Palomino-Schätzlein, Martina; Mesa, Jordi; Castaño, Justo P.; Luque, Raúl M.; Simó, Rafael (MDPI, 2019)

Insulin-like growth factor-1 (IGF-1) and growth hormone (GH) levels are the main targets for monitoring acromegaly activity, but they are not in close relationship with the clinical course of the disease and the associated ...

Molecular Characterization of Growth Hormone-producing Tumors in the GC Rat Model of Acromegaly

Martín, Juan Francisco; Muñoz-Bravo, José L.; Ibáñez-Costa, Alejandro; Fernández-Maza, Laura; Balcerzyk, Marcin; Leal Campanario, Rocío; Luque, Raúl M.; Castaño, Justo P.; Venegas-Moreno, Eva; Soto-Moreno, Alfonso; Leal-Cerro, Alfonso; Cano, David A. (Nature Research, 2015)

Acromegaly is a disorder resulting from excessive production of growth hormone (GH) and consequent increase of insulin-like growth factor 1 (IGF-I), most frequently caused by pituitary adenomas. Elevated GH and IGF-I levels ...