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Metabolic Fingerprint of Acromegaly and its Potential Usefulness in Clinical Practice
(MDPI, 2019)
Insulin-like growth factor-1 (IGF-1) and growth hormone (GH) levels are the main targets for monitoring acromegaly activity, but they are not in close relationship with the clinical course of the disease and the associated ...
Clinical Utility of Ghrelin-O-Acyltransferase (GOAT) Enzyme as a Diagnostic Tool and Potential Therapeutic Target in Prostate Cancer
(MDPI, 2019)
Recent data suggested that plasma Ghrelin O-Acyl Transferase enzyme (GOAT) levels could represent a new diagnostic biomarker for prostate cancer (PCa). In this study, we aimed to explore the diagnostic and prognostic/agg ...
3-Phenylcoumarins as Inhibitors of HIV-1 Replication
(MDPI, 2012)
We have synthesized fourteen 3-phenylcoumarin derivatives and evaluated their
anti-HIV activity. Antiviral activity was assessed on MT-2 cells infected with viral clones
carrying the luciferase gene as reporter. Inhibition ...
Complex I-Associated Hydrogen Peroxide Production Is Decreased and Electron Transport Chain Enzyme Activities Are Altered in n-3 Enriched fat-1 Mice
(Public Libray of Science (PLOS), 2010)
The polyunsaturated nature of n-3 fatty acids makes them prone to oxidative damage. However, it is not clear if n-3 fatty
acids are simply a passive site for oxidative attack or if they also modulate mitochondrial reactive ...
Extra-Virgin Olive Oil Modifies the Changes Induced in Non-Nervous Organs and Tissues by Experimental Autoimmune Encephalomyelitis Models
(MDPI, 2019)
This study reveals the existence of oxidative stress (reactive oxygen species (ROS)) in non-nervous organs and tissues in multiple sclerosis (MS) by means of a model of experimental autoimmune encephalomyelitis (EAE) in ...
Role of SST, CORT and ghrelin, and its receptors at the endocrine pancreas
(Frontiers In..., 2012)
CMV Latent Infection Improves CD8+ T Response to SEB Due to Expansion of Polyfunctional CD57+ Cells in Young Individuals
(Public Library of Science, 2014)
Cytomegalovirus (CMV) latent infection has a deleterious effect on the efficacy of influenza vaccination in the elderly,
suggesting that CMV restricts immunological diversity impairing the immune system functionality in ...
Diseño de una nueva asignatura dirigida al aprendizaje, integración y evaluación de competencias transversales en el grado de Medicina para la aplicación y mejora de su perfil laboral
(Consejo Social de la Universidad de Córdoba, 2012)
La propuesta presenta la creación de una nueva asignatura
en el grado de Medicina: Aplicación Clínica de las Ciencias
Médicas Básicas –cuyo desarrollo ha implicado una
inversión de 6.000 euros– que se imparte en el ...
DNAM-1 and the TIGIT/PVRIG/TACTILE Axis: Novel Immune Checkpoints for Natural Killer Cell-Based Cancer Immunotherapy
(MDPI, 2019)
Natural killer (NK) cells are lymphocytes of the innate immune response characterized by their role in the destruction of tumor cells. Activation of NK cells depend on a fine balance between activating and inhibitory signals ...
Los estudios veterinarios de D. Juan Darbón Díaz, el "médico de Platero"
(RACVAO, 2014)
Con este artículo queremos dar a conocer la vida académica, y el contexto en que esta se desarrolló, del Veterinario D.Juan Darbón Díaz, uno de los personajes que aparecen en la novela “Platero y yo”, obra en la que la ...