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Comparative insights of the kisspeptin/kisspeptin receptor system: lessons from non-mammalian vertebrates
(Elsevier, 2012)
Kisspeptins, the peptide products of the Kiss1 gene, were initially identified in mammals as ligands of the G protein‐coupled receptor 54 (GPR54; also termed Kiss1R) with ability to suppress tumor metastasis. In late 2003, ...
Hypothalamic mTOR Signaling Mediates the Orexigenic Action of Ghrelin
(Public Library Of Science (PLOS), 2012)
Current evidence suggests that ghrelin, a stomach derived peptide, exerts its orexigenic action through specific modulation
of Sirtuin1 (SIRT1)/p53 and AMP-activated protein kinase (AMPK) pathways, which ultimately increase ...
A PR-1-like Protein of Fusarium oxysporum Functions in Virulence on Mammalian Hosts
(American Society for Biochemistry and Molecular Biology Online, 2012)
The pathogenesis-related PR-1-like protein family comprises secreted proteins from the animal, plant, and fungal kingdoms whose biological function remains poorly understood. Here we have characterized a PR-1-like protein, ...
Genetic Footprints of Iberian Cattle in America 500 Years after the Arrival of Columbus
(Public Library of Science (PLOS), 2012)
Background: American Creole cattle presumably descend from animals imported from the Iberian Peninsula during the period of
colonization and settlement, through different migration routes, andmay have also suffered the ...
In vascular smooth muscle cells paricalcitol prevents phosphate-induced Wnt/β-catenin activation
(American Journal of Physiology, 2012)
The present study investigates the differential effect of two vitamin D receptor agonists, calcitriol and paricalcitol, on human aortic smooth muscle cells calcification in vitro. Human vascular smooth muscle cells were ...
Principles and Methodologies for the Determination of Shelf–Life in Foods
(INTECH, 2012)
The establishment of validated methodologies for the determination of food shelf-life is
currently demanded by both food industries and Health Authorities at national and
international scale. It is well known that most ...