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dc.contributor.authorRodríguez-Bies, Elizabeth
dc.contributor.authorSanta-Cruz Calvo, Sara
dc.contributor.authorFontán-Lozano, Ángela
dc.contributor.authorPeña Amaro, J.
dc.contributor.authorBerral de la Rosa, Francisco José
dc.contributor.authorCarrión, Ángel M.
dc.contributor.authorNavas, Plácido
dc.contributor.authorLópez-Lluch, Guillermo
dc.date.accessioned2013-07-15T08:53:20Z
dc.date.available2013-07-15T08:53:20Z
dc.date.issued2010
dc.identifier.urihttp://hdl.handle.net/10396/10727
dc.description.abstractEvery other day feeding (EOD) and exercise induce changes in cell metabolism. The aim of the present work was to know if both EOD and exercise produce similar effects on physical capacity, studying their physiological, biochemical and metabolic effects on muscle. Male OF-1 mice were fed either ad libitum (AL) or under EOD. After 18 weeks under EOD, animals were also trained by using a treadmill for another 6 weeks and then analyzed for physical activity. Both, EOD and endurance exercise increased the resistance of animals to extenuating activity and improved motor coordination. Among the groups that showed the highest performance, AL and EOD trained animals, ALT and EODT respectively, only the EODT group was able to increase glucose and triglycerides levels in plasma after extenuating exercise. No high effects on mitochondrial respiratory chain activities or protein levels neither on coenzyme Q levels were found in gastrocnemius muscle. However, exercise and EOD did increase b-oxidation activity in this muscle accompanied by increased CD36 levels in animals fed under EOD and by changes in shape and localization of mitochondria in muscle fibers. Furthermore, EOD and training decreased muscle damage after strenuous exercise. EOD also reduced the levels of lipid peroxidation in muscle. Our results indicate that EOD improves muscle performance and resistance by increasing lipid catabolism in muscle mitochondria at the same time that prevents lipid peroxidation and muscle damagees_ES
dc.format.mimetypeapplication/pdfes_ES
dc.language.isoenges_ES
dc.publisherPublic Library Of Science (PLOS)es_ES
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/4.0/es_ES
dc.sourcePLoS ONE 5 (11) (2010)es_ES
dc.subjectMicees_ES
dc.subjectPhysiologyes_ES
dc.subjectMuscle damagees_ES
dc.titleMuscle Physiology Changes Induced by Every Other Day Feeding and Endurance Exercise in Mice: Effects on Physical Performancees_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.rights.accessRightsinfo:eu-repo/semantics/openAccesses_ES


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