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Phosphorus restriction does not prevent the increase in fibroblast growth factor 23 elicited by high fat diet
(Public Library of Science, 2018)
This
study
was
designed
to evaluate
the
influence
of phosphorus
(P)
restriction
on
the
dele-
terious
effects
of high
fat
diets
on
mineral
metabolism.
Twenty-four
rats
were
allotted
to 3
groups
(n ...
Vitamin E protects against extraskeletal calcification in uremic rats fed high fat diets
(Biomed Central, 2017)
Background:
High fat diets are implicated in the pathogenesis of metabolic syndrome, obesity and renal disease.
Previous studies have revealed that high fat diets promote vascular calcification in uremic rats. Moreover, ...
Increased 1,25(OH)2-Vitamin D Concentrations after Energy Restriction Are Associated with Changes in Skeletal Muscle Phenotype
(MDPI, 2021)
The influence of energy restriction (ER) on muscle is controversial, and the mechanisms are not well understood. To study the effect of ER on skeletal muscle phenotype and the influence of vitamin D, rats (n = 34) were fed ...
Energy-dense diets increase FGF23, lead to phosphorus retention and promote vascular calcifications in rats
(Nature.com, 2016)
Rats with normal renal function (Experiment 1, n = 12) and uninephrectomized (1/2Nx) rats
(Experiment 2, n = 12) were fed diets with normal P (NP) and either normal (NF) or high fat (HF).
Rats with intact renal function ...
Caloric Intake in Renal Patients: Repercussions on Mineral Metabolism
(MDPI, 2020)
The aim of this paper is to review current knowledge about how calorie intake influences mineral metabolism focussing on four aspects of major interest for the renal patient: (a) phosphate (P) handling, (b) fibroblast ...
Hypocaloric Diet Prevents the Decrease in FGF21 Elicited by High Phosphorus Intake
(MDPI, 2018)
The effect of dietary phosphorus (P) on fibroblast growth factor 21 (FGF21)/ -klotho axis
was investigated in rats that were fed diets with: Normal (NP) or high P (HP) and either normal
(NC), high (HC) or low calories ...
Oral Acid Load Down-Regulates Fibroblast Growth Factor 23
(MDPI, 2022)
Increased dietary acid load has a negative impact on health, particularly when renal function is compromised. Fibroblast growth factor 23 (FGF23) is a bone-derived hormone that is elevated during renal failure. The ...