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dc.contributor.authorCardoso-Toset, Fernando
dc.contributor.authorGómez-Laguna, Fernando
dc.contributor.authorVela, Ana I.
dc.contributor.authorFernández-Garayzábal, F.
dc.contributor.authorLuque-Moreno, Inmaculada
dc.contributor.authorAmarilla, Shyrley P.
dc.contributor.authorCarrasco Otero, Librado
dc.contributor.authorAstorga Márquez, Rafael J.
dc.date.accessioned2017-01-26T09:39:53Z
dc.date.available2017-01-26T09:39:53Z
dc.date.issued2015
dc.identifier.urihttp://hdl.handle.net/10396/14439
dc.description.abstractTuberculosis-like lesions (TBL) in pigs have been associated with microorganisms other than mycobacteria. In this work a histopathological and microbiological evaluation of TBL in pigs is shown. A total of 352 samples belonging to 171 pigs totally condemned at slaughterhouse due to generalized TBL were sampled and selected for analysis. Pyogranulomatous (56.2%) and granulomatous lesions (20.2%) were observed in all analysed organs. Most of the granulomas observed in both lymph nodes and lungs belonged to more advanced stages of development (stages III and IV) whereas in the liver and the spleen most of lesions belonged to intermediate stages (stages II and III). Different microorganisms were simultaneously detected from TBL in the 42.7% of the animals. Mycobacterium tuberculosis complex (MTC) (38%), coryneform bacteria (40.3%) and streptococci (28.1%) were the main groups of microorganisms detected after bacteriological analysis, with Trueperella pyogenes and Streptococcus suis as the most frequently isolated species. Mycobacteria belonging to MTC were the most frequently detected pathogens in granulomatous and pyogranulomatous lesions in submandibular lymph nodes (32.7%) and coryneform bacteria were the microorganisms more frequently isolated from lungs (25.9%) and spleen samples (37.2%). These results may provide new insights into the pathogenesis and diagnosis of this pathology. The importance of coryneform bacteria and streptococci in such processes must be evaluated in future studieses_ES
dc.format.mimetypeapplication/pdfes_ES
dc.language.isoenges_ES
dc.publisherPublic Library of Sciencees_ES
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/4.0/es_ES
dc.sourcePLOS One, 10(9): e0139130es_ES
dc.subjectTuberculosis-like lesionses_ES
dc.subjectTBLes_ES
dc.subjectPigses_ES
dc.titleMulti-Etiological Nature of Tuberculosis-Like Lesions in Condemned Pigs at the Slaughterhousees_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.relation.publisherversionhttp://dx.doi.org/10.1371/journal.pone.0139130es_ES
dc.relation.projectIDJunta de Andalucía. AGR- 2685-2012es_ES
dc.relation.projectIDGobierno de España. (CDTI)-IDI-20111632/IDI-20111633es_ES
dc.rights.accessRightsinfo:eu-repo/semantics/openAccesses_ES


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