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Impact of the Content of Fatty Acids of Oral Fat Tolerance Tests on Postprandial Triglyceridemia: Systematic Review and Meta-Analysis
dc.contributor.author | Monfort-Pires, Milena | |
dc.contributor.author | Delgado-Lista, Javier | |
dc.contributor.author | Gómez Delgado, Francisco | |
dc.contributor.author | López-Miranda, José | |
dc.contributor.author | Pérez-Martínez, Pablo | |
dc.contributor.author | Gouvea Ferreira, Sandra Roberta | |
dc.date.accessioned | 2017-11-07T10:08:57Z | |
dc.date.available | 2017-11-07T10:08:57Z | |
dc.date.issued | 2016 | |
dc.identifier.uri | http://hdl.handle.net/10396/15331 | |
dc.description.abstract | Whether the content of saturated (SFA), monounsaturated (MUFA), and polyunsaturated fatty acids (PUFA) could differently influence postprandial triglycerides (TG) is unknown. We examined possible differences in the postprandial TG response to fat tolerance tests (FTTs), in which SFA or unsaturated fatty acids were used. Crossover clinical trials investigating the effects of FTTs containing SFA and unsaturated fats on postprandial triglyceridemia in databases from 1994 until 2016 were searched. Of 356 studies, 338 were excluded and 18 were considered. TG net incremental areas under the curve were calculated using time-points or changes from baseline. Pooled effects of standardized mean differences and I2 test were used. Results: In 12 studies, responses to SFA versus PUFA meals, and in 16 studies versus MUFA meals were compared. Over 4 hours, no differences between SFA and unsaturated fats were observed. Over 8 hours a lower response to PUFA (SMD −2.28; 95%CI −4.16, −0.41) and a trend to lower response to MUFA (SMD −0.89, 95%CI −1.82, 0.04) were detected. FTTs shorter than 8 hours may not be sufficient to differentiate postprandial TG after challenges with distinct fatty acids. Clinical significance of different postprandial TG responses on cardiovascular risk in the long-term deserves investigation. | es_ES |
dc.format.mimetype | application/pdf | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | MDPI | es_ES |
dc.rights | https://creativecommons.org/licenses/by/4.0/ | es_ES |
dc.source | Nutrients 8(9), 580 (2016) | es_ES |
dc.subject | Fat tolerance test | es_ES |
dc.subject | Postprandial triglycerides | es_ES |
dc.subject | Saturated fatty acids | es_ES |
dc.subject | Polyunsaturated fatty acids | es_ES |
dc.subject | Monounsaturated fatty acids | es_ES |
dc.title | Impact of the Content of Fatty Acids of Oral Fat Tolerance Tests on Postprandial Triglyceridemia: Systematic Review and Meta-Analysis | es_ES |
dc.type | info:eu-repo/semantics/article | es_ES |
dc.relation.publisherversion | https://doi.org/10.3390/nu8090580 | es_ES |
dc.relation.projectID | Gobierno de España. AGL2009-122270 | es_ES |
dc.relation.projectID | Gobierno de España. FIS PI10/01041 | es_ES |
dc.relation.projectID | Gobierno de España. FIS PI13/00023 | es_ES |
dc.relation.projectID | Gobierno de España. AGL2012/39615 | es_ES |
dc.relation.projectID | Junta de Andalucía. PI0193/09 | es_ES |
dc.relation.projectID | Junta de Andalucía. PI-0252/09 | es_ES |
dc.relation.projectID | Junta de Andalucía. PI-0058/10 | es_ES |
dc.relation.projectID | Junta de Andalucía. CVI-7450 | es_ES |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | es_ES |