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Surveillance of Drug-Resistant Tuberculosis in Spain (2001–2015)
| dc.contributor.author | Gutiérrez-Aroca, Juan-Bautista | |
| dc.contributor.author | Ruiz, Pilar | |
| dc.contributor.author | Vaquero Abellán, Manuel | |
| dc.contributor.author | Causse, Manuel | |
| dc.contributor.author | Casal Román, Manuel | |
| dc.date.accessioned | 2018-12-21T11:49:48Z | |
| dc.date.available | 2018-12-21T11:49:48Z | |
| dc.date.issued | 2018 | |
| dc.identifier.uri | http://hdl.handle.net/10396/17611 | |
| dc.description.abstract | Multidrug-resistant (MDR) tuberculosis (TB) is a cause of increasing concern. This study investigated first-line anti-TB drug resistance in Mycobacterium tuberculosis strains submitted to the Tuberculosis Reference Center in Co´rdoba (Spain) between 2001 and 2015. A total of 1,207 cultures were tested against first-line drugs using the BACTEC MGIT 960 system. Resistance to first-line drugs was detected in 207 strains (17.2%), the greatest resistance being found in INH (5.3%) followed by streptomycin (3%), pyrazinamide (2.2%), rifampicin (1%), and ethambutol (0.2%). A total of 1.9% of strains were MDR. Six strains displayed resistance to four drugs, and three strains to five drugs. In view of resistance observed, careful surveillance of drug resistance is recommended | es_ES |
| dc.format.mimetype | application/pdf | es_ES |
| dc.language.iso | eng | es_ES |
| dc.publisher | Mary Ann Liebert, Inc. | es_ES |
| dc.rights | https://creativecommons.org/licenses/by-nc-nd/4.0/ | es_ES |
| dc.source | Microbial Drug Resistance (2018) | es_ES |
| dc.subject | Tuberculosis | es_ES |
| dc.subject | Resistance | es_ES |
| dc.subject | Mycobacterium | es_ES |
| dc.title | Surveillance of Drug-Resistant Tuberculosis in Spain (2001–2015) | es_ES |
| dc.type | info:eu-repo/semantics/article | es_ES |
| dc.relation.publisherversion | https://doi.org/10.1089/mdr.2017.0353 | es_ES |
| dc.relation.projectID | Gobierno de España. REIPI RD06/0008 | es_ES |
| dc.rights.accessRights | info:eu-repo/semantics/openAccess | es_ES |
