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The Lin28/Let-7 System in Early Human Embryonic Tissue and Ectopic Pregnancy
(PLOS, 2014)
Our objective was to determine the expression of the elements of the Lin28/Let-7 system, and related microRNAs (miRNAs), in early stages of human placentation and ectopic pregnancy, as a means to assess the potential role ...
Progesterone receptor isoform A may regulate the effects of neoadjuvant aglepristone in canine mammary carcinoma
(BioMed Central, 2014)
Background: Progesterone receptors play a key role in the development of canine mammary tumours, and recent
research has focussed on their possible value as therapeutic targets using antiprogestins. Cloning and sequencing
of ...
Comparative insights of the kisspeptin/kisspeptin receptor system: lessons from non-mammalian vertebrates
(Elsevier, 2012)
Kisspeptins, the peptide products of the Kiss1 gene, were initially identified in mammals as ligands of the G protein‐coupled receptor 54 (GPR54; also termed Kiss1R) with ability to suppress tumor metastasis. In late 2003, ...
Rab18 Dynamics in Adipocytes in Relation to Lipogenesis, Lipolysis and Obesity
(Public Libray of Science (PLOS), 2011)
Lipid droplets (LDs) are organelles that coordinate lipid storage and mobilization, both processes being especially important
in cells specialized in managing fat, the adipocytes. Proteomic analyses of LDs have consistently ...
Metabolic Impact of Adult-Onset, Isolated, Growth Hormone Deficiency (AOiGHD) Due to Destruction of Pituitary Somatotropes
(Public Library Of Science (PLOS), 2011)
Growth hormone (GH) inhibits fat accumulation and promotes protein accretion, therefore the fall in GH observed with weight
gain and normal aging may contribute to metabolic dysfunction. To directly test this hypothesis ...
El uso de redes sociales como instrumento innovador en la educación universitaria: Facebook como herramienta de aprendizaje colaborativo en la asignatura de Inmunología
(UCOPress, 2018)
En la actualidad los docentes universitarios tienen el reto de enseñar a la conocida como “generación Y”, alumnos nacidos entre los años 1980 y 2000, los cuales no han conocido el mundo sin internet o teléfono móvil. Esto ...
Los Murciélagos del complejo Hundidero-Gato
(RACVAO, 2016)
Acciones tuteladas para la formación de profesorado novel: diseño e implementación de actividades y recursos de aprendizaje en soporte LMS
(UCOPress, 2018)
El presente artículo describe el desarrollo de un Proyecto formativo para la implementación de actividades y recursos de aprendizaje en la plataforma UCO-Moodle por parte de profesorado novel, bajo tutela y coordinación ...
Activation of microglia in specific hypothalamic nuclei and the cerebellum of adult rats exposed to neonatal overnutrition
(Blackwell Publishing, 2011)
Much attention has been drawn to the possible involvement of hypothalamic inflammation in the pathogenesis of metabolic disorders, especially in response to a high-fat diet. Microglia, the macrophages of the central nervous ...
Hypothalamic mTOR Signaling Mediates the Orexigenic Action of Ghrelin
(Public Library Of Science (PLOS), 2012)
Current evidence suggests that ghrelin, a stomach derived peptide, exerts its orexigenic action through specific modulation
of Sirtuin1 (SIRT1)/p53 and AMP-activated protein kinase (AMPK) pathways, which ultimately increase ...