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Olive Oil and the Hallmarks of Aging
(MDPI, 2016)
Aging is a multifactorial and tissue-specific process involving diverse alterations regardedas the “hallmarks of aging”, which include genomic instability, telomere attrition, epigenetic alterations, loss of proteostasis, ...
Glomerular Hematuria: Cause or Consequence of Renal Inflammation?
(MDPI, 2019)
Glomerular hematuria is a cardinal symptom of renal disease. Glomerular hematuria may be classified as microhematuria or macrohematuria according to the number of red blood cells in urine. Recent evidence suggests a ...
Protective Role of Nrf2 in Renal Disease
(MDPI, 2020)
Chronic kidney disease (CKD) is one of the fastest-growing causes of death and is predicted to become by 2040 the fifth global cause of death. CKD is characterized by increased oxidative stress and chronic inflammation. ...
Coenzyme Q10 Supplementation for the Reduction of Oxidative Stress: Clinical Implications in the Treatment of Chronic Diseases
(MDPI, 2020)
Apart from its main function in the mitochondria as a key element in electron transport, Coenzyme Q10 (CoQ10) has been described as having multiple functions, such as oxidant action in the generation of signals and the ...
Role of Toll-like receptor 4 in intravascular hemolysis-mediated injury
(Wiley, 2022)
Massive intravascular hemolysis is a common characteristic of several pathologies. It is associated with the release of large quantities of heme into the circulation, promoting injury in vulnerable organs, mainly kidney, ...