Postoperative Analgesic Effects Of Dexketoprofen, Buprenorphine And Tramadol In Dogs Undergoing Ovariohysterectomy

Abstract

The objective of this study was to compare the postoperative analgesic effects of dexketoprofen, trama- dol, and buprenorphine in dogs undergoing ovariohysterectomy. Seventy-five adult female dogs were randomly assigned to receive an intravenous injection (IV) of 1 mg/kg of dexketoprofen (D), 0.02 mg/ kg of buprenorphine (B) or 2 mg/kg of tramadol (T). Pain assessment was performed during 48 h after ovariohysterectomy using a dynamic interactive visual analogue scale (DIVAS) and Glasgow composite measure pain scale (CMPS-SF). Rescue analgesia was required in 43%, 21%, and 5% of dogs in the B, T, and D groups, respectively, with significant differences between B and D (p = 0.010) groups. The DIVAS and CMPS-SF values of the B group were significantly higher than those of the T and D groups. The most common undesirable effect was dysphoria in dexketoprofen group. Tramadol and dexketoprofen provide superior postoperative analgesia compared with buprenorphine in dogs undergoing ovariohysterectomy.