Accelerating FaST-LMM for Epistasis Tests

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Author
Martínez, Héctor
Barrachina, Sergio
Castillo, Maribel
Quintana-Ortí, Enrique S.
Rambla De Argila, Jordi
Ferré, Xavier
Navarro, Arcadi
Publisher
Springer NatureDate
2017Subject
EpistasisFaST-LMM
High-performance computing
Multithreaded parallelism
Graphics processors
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Show full item recordAbstract
We introduce an enhanced version of FaST-LMM that main-
tains the sensitivity of this software when applied to identify epistasis
interactions while delivering an acceleration factor that is close to 7.5×
on a server equipped with a state-of-the-art graphics coprocessor. This
performance boost is obtained from the combined effects of integrating
a dictionary for faster storage of the test results; a re-organization of the
original FaST-LMM Python code; and off-loading of compute-intensive
parts to the graphics accelerator.
