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Immune signatures of pathogenesis in the peritoneal compartment during early infection of sheep with Fasciola hepatica
(Nature, 2017)
Immune signatures of sheep acutely-infected with Fasciola hepatica, an important pathogen of
livestock and humans were analysed within the peritoneal compartment to investigate early infection.
Within the peritoneum, F. ...
Understanding Spatio-Temporal Variability in the Reproduction Ratio of the Bluetongue (BTV-1) Epidemic in Southern Spain (Andalusia) in 2007 Using Epidemic Trees
(Public Library of Science, 2016)
Andalusia (Southern Spain) is considered one of the main routes of introduction of bluetongue
virus (BTV) into Europe, evidenced by a devastating epidemic caused by BTV-1 in
2007. Understanding the pattern and the drivers ...
Identification of reference genes for real-time PCR cytokine gene expression studies in sheep experimentally infected with Fasciola hepatica
(Nature.com, 2019)
The aim of this study was to validate reference genes for gene normalisation using qRT-PCR in hepatic lymph nodes (HLN) and livers from sheep infected with Fasciola hepatica during early and late stages of infection. To ...
Fasciola hepatica induces eosinophil apoptosis in the migratory and biliary stages of infection in sheep
(Elsevier, 2016)
The aim of the present work was to evaluate the number of apoptotic eosinophils in the livers of sheep experimentally infected with Fasciola hepatica during the migratory and biliary stages of infection. Four groups (n = ...
Distribution of Foxp3+ T cells in the liver and hepatic lymph nodes of goats and sheep experimentally infected with Fasciola hepatica
(Elsevier, 2016)
Foxp3 regulatory T cells (Tregs) are now considered to play a key role in modulation of immune responses during parasitic helminth infections. Immunomodulation is a key factor in Fasciola hepatica infection; however, the ...
Apoptosis of peritoneal leucocytes during early stages of Fasciola hepatica infections in sheep
(Elsevier, 2017)
Several immunomodulatory properties have been described in Fasciola hepatica infections. Apoptosis has been shown to be an effective mechanism to avoid the immune response in helminth infections. The aim of the present ...