Listar Departamento de Biología Celular, Fisiología e Inmunología por autor "346fd0b8-7635-4fa6-ae94-3b42b3f6c3ed"
Mostrando ítems 1-2 de 2
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Characterization of the DNAM-1, TIGIT and TACTILE Axis on Circulating NK, NKT-Like and T Cell Subsets in Patients with Acute Myeloid Leukemia
Valhondo, Isabel; Hassouneh, Fakhri; López-Sejas, Nelson; Pera Rojas, Alejandra; Sánchez-Correa, Beatriz; Guerrero, Beatriz; Bergua, Juan M.; Arcos, María José; Bañas, Helena; Casas-Avilés, Ignacio; Sánchez García, Joaquín; Serrano, Josefina; Martín, Carmen; Durán, Esther; Alonso, Corona; Solana Lara, Rafael; Tarazona, Raquel (MDPI, 2020)Background: Acute myeloid leukemia (AML) remains a major clinical challenge due to poor overall survival, which is even more dramatic in elderly patients. TIGIT, an inhibitory receptor that interacts with CD155 and CD112 ... -
DNAM-1 and the TIGIT/PVRIG/TACTILE Axis: Novel Immune Checkpoints for Natural Killer Cell-Based Cancer Immunotherapy
Sánchez-Correa, Beatriz; Valhondo, Isabel; Hassouneh, Fakhri; López-Sejas, Nelson; Pera Rojas, Alejandra; Bergua, Juan M.; Arcos, María José; Bañas, Helena; Casas-Avilés, Ignacio; Durán, Esther; Alonso, Corona; Solana Lara, Rafael; Tarazona, Raquel (MDPI, 2019)Natural killer (NK) cells are lymphocytes of the innate immune response characterized by their role in the destruction of tumor cells. Activation of NK cells depend on a fine balance between activating and inhibitory signals ...