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The Lin28/Let-7 System in Early Human Embryonic Tissue and Ectopic Pregnancy
(PLOS, 2014)
Our objective was to determine the expression of the elements of the Lin28/Let-7 system, and related microRNAs (miRNAs), in early stages of human placentation and ectopic pregnancy, as a means to assess the potential role ...
Ghrelin-O-Acyltransferase (GOAT) Enzyme as a Novel Potential Biomarker in Gastroenteropancreatic Neuroendocrine Tumors
(Nature.com, 2018)
Objectives: The association between the presence and alterations of the components of the ghrelin system and the
development and progression of neuroendocrine tumors (NETs) is still controversial and remains unclear.
Methods: ...
Novel diagnostic biomarkers and therapeutic options for neuroendocrine tumors
(Universidad de Córdoba, UCOPress, 2019)
Neuroendocriene tumoren (NET) vormen een heterogene groep van zeldzaam voorkomende, langzaam groeiende tumoren. NET ontstaan vanuit enterochromaffine cellen. De jaarlijkse incidentie van NET is progressief toegenomen in ...
Identification of novel endocrine-metabolic and splicing machinery factors with diagnostic, prognostic and/or therapeutic potential in prostate cancer
(Universidad de Córdoba, UCOPress, 2020)
Prostate cancer (PCa) is the tumor pathology with the highest incidence among men in developed countries and represents one of the main causes of cancer-related death in this group. Despite the advances achieved during the ...
Identification of novel clinical and molecular factors for the diagnosis and aggressiveness of prostate cancer
(Universidad de Córdoba, UCOPress, 2019)
Prostate cancer (PCa) is the most common solid neoplasm in men in developed countries. Unfortunately, the extraordinary heterogeneity and complexity of PCa, together with its phenotypic/clinical variability, strongly ...
Mediators of the cellular response to the development of obesity and metabolic disease
(Universidad de Córdoba, UCOPress, 2021)
Obesity is the pandemic of the 21st century. Overall, about 15% of the world’s adult population is obese, and if the rising trend continues, it is estimated that global prevalence reaches 20% by 2025. Obesity poses a major ...
Implication of the alternative splicing process in the development of hepatocelular carcinoma
(Universidad de Córdoba, UCOPress, 2021)
Liver cancer represents a complex and heterogeneous pathology that encompasses several types of malignant tumors with unfavorable characteristics and prognosis, including hepatocellular carcinoma or hepatocarcinoma (HCC). ...
Molecular and Clinical Implications of Somatostatin Receptor Profile and Somatostatin Analogues Treatment in Oral Cavity Squamous Cell Carcinoma
(MDPI, 2021)
Oral squamous cell carcinoma (OSCC) incidence has increased by 50% over the last decade. Unfortunately, surgery and adjuvant radiotherapy and chemotherapy are still the mainstream modality of treatment, underscoring the ...
Novel molecular insights on the role of splicing dysregulation in cancer
(Universidad de Córdoba, UCOPress, 2022)
Cancer and tumoral diseases represent one of most serious and complicated public health problems, being one of the leading causes of death in the world. The remarkable variety across cancer types, and the heterogeneity ...
Molecular, cellular and anatomopathological study of oral cavity tumors
(Universidad de Córdoba, UCOPress, 2022)
Oral cavity squamous cell carcinoma (OSCC) continues to be an aggressive disease and a global challenge with a 5-year survival rate of 60%. Depending on the risk factors, surgery and adjuvant radiotherapy +/- chemotherapy ...