Buscar
Mostrando ítems 1-10 de 28
Identification of Novel Markers and Molecular Mechanisms with Diagnostic, Prognostic, and Therapeutic Potential in Brain Tumors
(Universidad de Córdoba, UCOPress, 2022)
Primary brain tumors represent a highly variable and heterogeneous group of neoplasms (~150 different types) that includes non-malignant and malignant tumors. The most frequent malignant brain tumors are gliomas (representing ...
Papel de la Citocromo b5 reductasa-3 (CYB5R3) y del componente graso de la dieta en la fisiología y el envejecimiento del músculo esquelético
(Universidad de Córdoba, UCOPress, 2022)
El envejecimiento es el declive progresivo dependiente del tiempo que viene acompañado de una disminución de la fertilidad y del aumento de la susceptibilidad del organismo a amenazas tanto endógenas como externas. A lo ...
Determination of new DYRK2 functions in response to genotoxic stress
(Universidad de Córdoba, UCOPress, 2022)
Cancer is a complex disease enhanced by alterations in signaling pathways. In fact, DNA damage response (DDR) pathways play a key role in cancer development when they are deregulated. DDR pathways induce a cellular response ...
Somatostatin Receptor Splicing Variant sst5TMD4 Overexpression in Glioblastoma Is Associated with Poor Survival, Increased Aggressiveness Features and Somatostatin Analogs Resistance
(MDPI, 2022)
Glioblastoma (GBM) is the most malignant and lethal brain tumor. Current standard treatment consists of surgery followed by radiotherapy/chemotherapy; however, this is only a palliative approach with a mean post-operative ...
CCN2 Binds to Tubular Epithelial Cells in the Kidney
(MDPI, 2022)
Cellular communication network-2 (CCN2), also called connective tissue growth factor (CTGF), is considered a fibrotic biomarker and has been suggested as a potential therapeutic target for kidney pathologies. CCN2 is a ...
Papel etiopatogénico e implicaciones diagnósticas de microRNAs en el síndrome de ovario poliquístico
(Universidad de Córdoba, UCOPress, 2022)
1. Introducción o motivación de la tesis: El síndrome de ovario poliquístico (SOP) es una enfermedad de alta prevalencia que afecta al 5-10% del total de mujeres en edad reproductiva, cuyos síntomas se inician habitualmente ...
Sistemas de detección ultrasensible de moléculas de distinta naturaleza para la detección temprana del cáncer
(Universidad de Córdoba, UCOPress, 2022)
La técnica ELISA (del inglés “enzyme-linked immunosorbent assay”) es el método de rutina más utilizado y fiable para la detección de marcadores proteicos relevantes en la asistencia sanitaria. Aumentar la sensibilidad de ...
Evaluation of Two Equations for Prediction of Digestible Energy in Mixed Feeds and Diets for Horses
(MDPI, 2022)
Several authors have developed equations for estimating digestible energy in horse feeds as an alternative to the inconveniences of in vivo digestibility assays. We aimed to evaluate two of such equations. A dataset was ...
Valor pronóstico del estudio molecular en la enfermedad de Cushing
(Universidad de Córdoba, UCOPress, 2022)
La enfermedad de Cushing (EC) se origina por un tumor hipofisario secretor de hormona adrenocorticotrópica (ACTH), que suele presentarse en forma de microadenoma en el 95% de los casos. Los tumores hipofisarios secretores ...
Morphofunctional and Molecular Assessment of Nutritional Status in Head and Neck Cancer Patients Undergoing Systemic Treatment: Role of Inflammasome in Clinical Nutrition
(MDPI, 2022)
Malnutrition in patients with head and neck cancer is frequent, multifactorial and widely associated with clinical evolution and prognosis. Accurate nutritional assessments allow for early identification of patients at ...