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Identification of Potential New Protein Vaccine Candidates through Pan-Surfomic Analysis of Pneumococcal Clinical Isolates from Adults 

Olaya-Abril, Alfonso; Jiménez-Munguía, I.; Gómez-Gascón, Lidia; Obando, Ignacio; Rodríguez-Ortega, Manuel J. (Public Library of Science, 2013)
Purified polysaccharide and conjugate vaccines are widely used for preventing infections in adults and in children against the Gram-positive bacterium Streptococcus pneumoniae, a pathogen responsible for high morbidity ...
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Proteomic analysis of goat milk kefir: profiling the fermentation-time dependent protein digestion and identification of potential peptides with biological activity 

Izquierdo-González, Juan J.; Amil-Ruiz, Francisco; Zazzu, Sabina; Sánchez-Lucas, Rosa; Fuentes-Almagro, Carlos; Rodríguez-Ortega, Manuel J. (Elsevier, 2019)
Kefir is a fermented dairy product, associated to health benefits because of being a probiotic and due to the presence of molecules with biological activity. In this work, we have profiled the peptide composition of goat ...
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Search of Potential Vaccine Candidates against Trueperella pyogenes Infections through Proteomic and Bioinformatic Analysis 

Galán Relaño, Ángela; Gómez-Gascón, Lidia; Rodríguez-Franco, Antonio; Luque, Inmaculada; Huerta Lorenzo, Belén; Tarradas-Iglesias, Carmen; Rodríguez-Ortega, Manuel J. (MDPI, 2020)
Trueperella pyogenes is an opportunistic pathogen, responsible for important infections in pigs and significant economic losses in swine production. To date, there are no available commercial vaccines to control diseases ...
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Characterization of the Burkholderia cenocepacia J2315 Surface-Exposed Immunoproteome 

Sousa, Sílvia A.; Seixas, António M.M.; Mandal, Manoj; Rodríguez-Ortega, Manuel J.; Leitão, Jorge H. (MDPI, 2020)
Infections by the Burkholderia cepacia complex (Bcc) remain seriously life threatening to cystic fibrosis (CF) patients, and no effective eradication is available. A vaccine to protect patients against Bcc infections is a ...
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Comparative Exoproteome Analysis of Streptococcus suis Human Isolates 

Prados de la Torre, Esther; Rodríguez-Franco, Antonio; Rodríguez-Ortega, Manuel J. (MDPI, 2021)
The swine pathogen Streptococcus suis is a Gram-positive bacterium which causes infections in pigs, with an impact in animal health and in the livestock industry, and it is also an important zoonotic agent. During the ...
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Approaching In Vivo Models of Pneumococcus–Host Interaction: Insights into Surface Proteins, Capsule Production, and Extracellular Vesicles 

Olaya-Abril, Alfonso; González Reyes, José Antonio; Rodríguez-Ortega, Manuel J. (MDPI, 2021)
Infections caused by the Gram-positive bacterium Streptococcus pneumoniae have become a major health problem worldwide because of their high morbidity and mortality rates, especially in developing countries. This microorganism ...
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Extracellular Vesicles from Different Pneumococcal Serotypes Are Internalized by Macrophages and Induce Host Immune Responses 

Olaya-Abril, Alfonso; Prados Rosales, Rafael; González Reyes, José Antonio; Casadevall, Arturo; Pirofski, Liise-anne; Rodríguez-Ortega, Manuel J. (MDPI, 2021)
Bacterial extracellular vesicles are membranous ultrastructures released from the cell surface. They play important roles in the interaction between the host and the bacteria. In this work, we show how extracellular vesicles ...
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Overcoming function annotation errors in the Gram-positive pathogen Streptococcus suis by a proteomics-driven approach 

Rodríguez-Ortega, Manuel J.; Luque-Moreno, Inmaculada; Tarradas-Iglesias, Carmen; Bárcena Ruiz, José Antonio (BioMed Central, 2008)
Background: Annotation of protein-coding genes is a key step in sequencing projects. Protein functions are mainly assigned on the basis of the amino acid sequence alone by searching of homologous proteins. However, fully ...
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Detection of redox modified proteins by gel-free proteomics 

McDonagh, B.; Ogueta-Villarreal, Samuel; Padilla, A.; Lasarte, G.; Rodríguez-Ortega, Manuel J.; Bárcena Ruiz, José Antonio (Universidad de Córdoba, Servicio de Publicaciones, 2008)
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Identification of new immunoprotective surface protein vaccine candidates against streptococcus suis infection by proteomics 

Gómez-Gascón, Lidia; Olaya-Abril, Alfonso; Jiménez-Munguía, I.; Luque-Moreno, Inmaculada; Tarradas-Iglesias, Carmen; Bárcena Ruiz, José Antonio; Rodríguez-Ortega, Manuel J. (Universidad de Córdoba, Servicio de Publicaciones, 2011)

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Rodríguez-Ortega, Manuel J. (10)
Olaya-Abril, Alfonso (4)Bárcena Ruiz, José Antonio (3)Gómez-Gascón, Lidia (3)Tarradas-Iglesias, Carmen (3)González Reyes, José Antonio (2)Jiménez-Munguía, I. (2)Luque-Moreno, Inmaculada (2)Amil-Ruiz, Francisco (1)Casadevall, Arturo (1)... View MoreSubjectProteomics (3)Biotecnología (2)Host-pathogen interaction (2)Membrane vesicles (2)Proteómica (2)Sistemas biológicos (2)Streptococcus suis (2)Surface proteins (2)Antigens (1)Burkholderia cepacia complex (1)... View MoreDate Issued2020 - 2021 (5)2010 - 2019 (3)2008 - 2009 (2)

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