Departamento de Biología Celular, Fisiología e Inmunología

 

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  • Changes in quantity plant‑based protein intake on type 2 diabetes remission in coronary heart disease patients: from the CORDIOPREV study 

    Gutiérrez Mariscal, Francisco Miguel; Alcalá-Diaz, Juan F.; Quintana-Navarro, Gracia M.; Cruz Ares, Silvia de la; Torres‑Peña, J.D.; Cardelo, Magdalena P.; Arenas de Larriva, Antonio P.; Malagón, María M.; Romero-Cabrera, Juan Luis; Ordovás, José María; Pérez Martínez, Pablo; Delgado-Lista, Javier; Yubero-Serrano, Elena M.; López Miranda, José; López Miranda (Springer, 2023)
    Purpose: Diabetes remission is a phenomenon described in the context of drastic weight loss due to bariatric surgery or low-calorie diets. Evidence suggests that increasing the intake of plant protein could reduce the risk ...

  • Intravascular hemolysis triggers NAFLD characterized by a deregulation of lipid metabolism and lipophagy blockade 

    Rayego-Mateos, Sandra; Morgado-Pascual, José Luis; García-Caballero, Cristina; Lázaro, Iolanda; Sala-Vila, Aleix; Opazo-Ríos, Lucas; Mas-Fontao, Sebastián; Egido, J.; Ruiz-Ortega, Marta; Moreno, Juan Antonio (Wiley, 2023)
    Intravascular hemolysis is a common feature of different clinical entities, including sickle cell disease and malaria. Chronic hemolytic disorders are associated with hepatic damage; however, it is unknown whether heme ...

  • Splicing Machinery Is Impaired in Oral Squamous Cell Carcinomas and Linked to Key Pathophysiological Features 

    Sanjuan-Sanjuan, Alba; Alors-Pérez, Emilia; Sánchez-Frías, Marina; Monserrat-Barbudo, José A.; Falguera Uceda, Mabel; Heredero-Jung, Susana; Luque, Raúl M. (MDPI, 2024)
    Alternative splicing dysregulation is an emerging cancer hallmark, potentially serving as a source of novel diagnostic, prognostic, or therapeutic tools. Inhibitors of the activity of the splicing machinery can exert ...

  • Impact of Cognitive Impairment on Quality of Life in Multiple Sclerosis Patients—A Comprehensive Review 

    Gómez-Melero, Sara; Caballero-Villarraso, Javier; Escribano, Begoña M.; Galvao-Carmona, Alejandro; Túnez, Isaac; Agüera Morales, Eduardo (MDPI, 2024)
    Multiple sclerosis (MS) is characterized by a variety of symptoms that have a major impact on quality of life (QoL) even in early stages. In addition to individual motor, sensory, visual disturbances, and brainstem and ...

  • Preclinical Characterization of Pharmacologic NAD+Boosting as a Promising Therapeutic Approach inRheumatoid Arthritis 

    Pérez Sánchez, Carlos; Escudero Contreras, Alejandro; Cerdó, Tomás; Sánchez-Mendoza, Luz Marina; Llamas Urbano, Adrián; Arias de la Rosa, Iván; Pérez Rodríguez, Miguel; Muñoz-Barrera, Laura; Ábalos-Aguilera, María del Carmen; Barbarroja, Nuria; Calvo Gutiérrez, Jerusalém; Ortega Castro, María Rafaela; Ruiz-Vilchez, Desirée; Moreno, Juan Antonio; Burón, Isabel; González Reyes, José Antonio; López-Pedrera, Ch.; Villalba, José Manuel (Wiley, 2023)
    Objective: We analyzed NAD+ metabolism in patients with rheumatoid arthritis (RA), its association with disease activity and clinical outcomes of RA, and the therapeutic potential of pharmacologic NAD+ boosting. Methods: ...

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