Listar Departamento de Genética por título
Mostrando ítems 692-711 de 736
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Targeted DNA demethylation in human cells by fusion of a plant 5-methylcytosineDNA glycosylase to a sequence-specific DNA binding domain
(Taylor & Francis, 2017)DNA methylation is a crucial epigenetic mark associated to gene silencing, and its targeted removal is amajor goal of epigenetic editing. In animal cells, DNA demethylation involves iterative 5mC oxidation byTET enzymes ... -
Targeting Iron Acquisition Blocks Infection with the Fungal Pathogens Aspergillus fumigatus and Fusarium oxysporum
(Public Library of Science, 2013)Filamentous fungi are an important cause of pulmonary and systemic morbidity and mortality, and also cause corneal blindness and visual impairment worldwide. Utilizing in vitro neutrophil killing assays and a model of ... -
Targeting metabolism to improve immunotherapy in gsnor-deficient colorectal cancer
(Universidad de Córdoba, UCOPress, 2024)Colorectal cancer (CRC) is the third most diagnosed type of cancer and the second leading cause of cancer death worldwide. Despite the increasing knowledge of CRC molecular biology and the development of new targeted ... -
Terneros de raza retinta en cebadero: análisis individual y por lotes
(Federación Española de Asociaciones de Ganado Selecto, 2004)La raza Retinta dispone de un censo aproximado de 200.000 reproductoras de las cuales más de un 10% están inscritas en el Libro Genealógico de la raza. Representa el 5,3% del bovino español y el 14,5% del autóctono. En ... -
The Bovine Pangenome Consortium: democratizing production and accessibility of genome assemblies for global cattle breeds and other bovine species
(BioMed Central (Springer), 2023)The Bovine Pangenome Consortium (BPC) is an international collaboration dedicated to the assembly of cattle genomes to develop a more complete representation of cattle genomic diversity. The goal of the BPC is to provide ... -
The crucial role of breeder and dog owners associations in safeguarding genetic heritage of endangered Balearic dog breeds: gender preference and registry adscription
(MDPI, 2024)This study delves into the complex relationships between indigenous dog breeds in the Balearic Isles and their human counterparts, specifically breeders and owners. Using Canonical Correlation Analysis, the research examines ... -
The DNA Repair Protein XRCC1 Functions in the Plant DNA Demethylation Pathway by Stimulating Cytosine Methylation (5-meC) Excision, Gap Tailoring, and DNA Ligation
(JBC, 2013)Background: Active DNA demethylation in plants is initiated by 5-meC DNA glycosylases of the ROS1/DME family and continued through a base excision repair pathway. Results: XRCC1 stimulates ROS1-initiated demethylation ... -
The Fusarium oxysporum gnt2, Encoding a Putative NAcetylglucosamine Transferase, Is Involved in Cell Wall Architecture and Virulence
(Public Library of Science, 2013)With the aim to decipher the molecular dialogue and cross talk between Fusarium oxysporum f.sp. lycopersci and its host during infection and to understand the molecular bases that govern fungal pathogenicity, we analysed ... -
The Gal4-Type Transcription Factor Pro1 Integrates Inputs from Two Different MAPK Cascades to Regulate Development in the Fungal Pathogen Fusarium oxysporum
(MDPI, 2022)Mitogen-activated protein kinase (MAPK) signaling pathways control fundamental aspects of growth and development in fungi. In the soil-inhabiting ascomycete Fusarium oxysporum, which causes vascular wilt disease in more ... -
The homeodomain transcription factor Ste12: Connecting fungal MAPK signalling to plant pathogenicity
(Landes Bioscience, 2010)A conserved mitogen-activated protein kinase (MAPK) cascade orthologous to the mating/filamentation MAPK pathway in yeast is required for fungal pathogenicity on plants. One of the key targets of this signalling pathway ... -
The Secreted Peptide PIP1 Amplifies Immunity through Receptor-Like Kinase 7
(Public Library of Science, 2014)In plants, innate immune responses are initiated by plasma membrane-located pattern recognition receptors (PRRs) upon recognition of elicitors, including exogenous pathogen-associated molecular patterns (PAMPs) and endogenous ... -
The Semen Microbiome and Semen Parameters in Healthy Stallions
(MDPI, 2022)Despite the advances in reproductive technology, there is still a considerable number of low sperm quality cases in stallions. Recent studies in humans have detected several seminal microflora–spermatozoa associations ... -
The Southwestern fringe of Europe as an important reservoir of caprine biodiversity
(BioMed Central, 2015)Background. Portugal and Spain, with six and 22 officially recognized caprine breeds, encompass 25 % of the European Union goat census. Many of these populations have suffered strong demographic declines because of competition ... -
The Study of Growth and Performance in Local Chicken Breeds and Varieties: A Review of Methods and Scientific Transference
(MDPI, 2021)A review of the scientific advances in the study of the growth and performance in native chicken breeds and varieties over the past 20 years was performed. Understanding the growth patterns of native breeds can only be ... -
The Winner Takes it All: Risk Factors and Bayesian Modelling of the Probability of Success in Escaping from Big Cat Predation
(MDPI, 2021)The individuals engaged in predation interactions modify their adaptation strategies to improve their efficiency to reach success in the fight for survival. This success is linked to either capturing prey (predator) or ... -
The Youngest, the Heaviest and/or the Darkest? Selection Potentialities and Determinants of Leadership in Canarian Dromedary Camels
(MDPI, 2021)Several idiosyncratic and genetically correlated traits are known to extensively influence leadership in both domestic and wild species. For minor livestock such as camels, however, this type of behavior remains loosely ... -
Tipos hemoglobínicos en équidos
(Universidad de Córdoba, Servicio de Publicaciones, 1978)Horses of the english, the spanish•and the arabian thoroitg bred, had been studied conceming the haernoglobinic polyrnorphism. The geneic and genotype frecuencyes are expressed, having found significant differences between ... -
Toxicological and Epigenetic Studies of Two Types of Ale Beer, Tyrosol and Iso-Alpha Humulone
(MDPI, 2021)Although many benefits drawn from beer consumption are claimed, the epidemiological records are contradictory with respect to cancer prevention. The purpose of this study was to investigate the possible health-related ... -
Toxicological and Nutraceutical Screening Assays of Some Artificial Sweeteners
(MDPI, 2022)Artificial sweeteners are food additives worldwide used instead of fructose or glucose in many diet beverages. Furthermore, diet beverages intake has been increasing every year. Thus, some food agencies should regulate it ... -
Toxicological Studies of Czech Beers and Their Constituents
(MDPI, 2019)Background: Czech beers are unique because they are brewed using specific technology at a particular latitude and for being entirely produced in the area of the Czech Republic. The purpose of this work is the evaluation ...