• Aglepristone decreases proliferation in progesterone receptor-positive canine mammary carcinomas 

      Guil-Luna, Silvia; Sánchez Céspedes, Raquel; Millán, Yolanda; De Andrés, Francisco Javier; Rollón, Eva; Domingo, Victor; Guscetti, Franco; Martín de las Mulas González-Albo, Juana (Wiley, 2011)
      Progesterone receptor (PR) antagonist aglepristone (RU534) has been used successfully for pregnancy termination and therapy of pyometra, vaginal tumors, and mammary hyperplasia in bitches and queens. All of these conditions ...
    • Expression of the Short Form of RON/STK in Feline Mammary Carcinoma 

      Maniscalco, Lorella; Guil-Luna, Silvia; Lussich, Selina; Gattino, Francesca; Trupia, Calogero; Millán, Yolanda; Martín de las Mulas González-Albo, Juana; Sánchez Céspedes, Raquel; Saeki, Kino; Accornero, Paolo; De María, Rafaella (Sage, 2019)
      RON is a tyrosine kinase receptor activated by the macrophage-stimulating protein (MSP) ligand that is overexpressed in human breast cancer. In humans, RON protein can be present in different isoforms, and the most studied ...
    • Isolation, purification, culture and characterisation of myoepithelial cells from normal and neoplastic canine mammary glands using a magnetic-activated cell sorting separation system 

      Sánchez-Céspedes, Raquel; Maniscalco, Lorella; Lussich, Selina; Martignani, Eliane; De María, Rafaella; Martín de las Mulas González-Albo, Juana; Martín de las Mulas González-Albo, Juana; Millán, Yolanda (Elsevier, 2013)
      Mammary gland tumours, the most common malignant neoplasm in bitches, often display myoepithelial (ME) cell proliferation. The aim of this study was to isolate, purify, culture and characterise ME cells from normal and ...
    • Myoepithelial cell layer integrity in canine mammary carcinoma 

      Sánchez-Céspedes, Raquel; Millán, Yolanda; Guil-Luna, Silvia; García-Monterde, J.; Reymundo, Carlos; Espinosa de los Monteros, Antonio; Martín de las Mulas González-Albo, Juana (Elsevier, 2011)
      The aim of this study was to determine whether the myoepithelial (ME) cell marker calponin could be used to analyze the integrity of the ME cell layer as a means of identifying canine mammary carcinoma in situ. Tissue from ...
    • Myoepithelial cells in canine mammary tumours 

      Sánchez-Céspedes, Raquel; Millán, Yolanda; Guil-Luna, Silvia; Reymundo, Carlos; Espinosa de los Monteros, Antonio; Martín de las Mulas González-Albo, Juana (Elsevier, 2016)
      Mammary tumours are the most common neoplasms of female dogs. Compared to mammary tumours of humans and cats, myoepithelial (ME) cell involvement is common in canine mammary tumours (CMT) of any subtype. Since ME cell ...
    • Progesterone receptor isoform A may regulate the effects of neoadjuvant aglepristone in canine mammary carcinoma 

      Guil-Luna, Silvia; Stenvang, Jan; Brünner, Nils; De Andrés, Francisco Javier; Sánchez Céspedes, Raquel; Millán, Yolanda; Martín de las Mulas González-Albo, Juana (BioMed Central, 2014)
      Background: Progesterone receptors play a key role in the development of canine mammary tumours, and recent research has focussed on their possible value as therapeutic targets using antiprogestins. Cloning and sequencing of ...
    • Progesterone Receptor Isoform Analysis by Quantitative Real-Time Polymerase Chain Reaction in Formalin-Fixed, Paraffin-Embedded Canine Mammary Dysplasias and Tumors 

      Guil-Luna, Silvia; Stenvang, Jan; Brünner, Nils; Sánchez Céspedes, Raquel; Millán, Yolanda; Gómez-Laguna, J.; Martín de las Mulas González-Albo, Juana (Sage, 2014)
      Cloning and sequencing of the progesterone receptor gene in dogs have revealed 2 isoforms, A and B, transcribed from a single gene. Distribution of isoforms A and B in canine mammary lesions has hitherto been investigated ...
    • Sex Steroid Hormones and Tumors in Domestic Animals 

      Millán, Yolanda; Guil-Luna, Silvia; Sánchez-Céspedes, Raquel; Martín de las Mulas González-Albo, Juana (Intech, 2013)
      Sex steroid hormones play a role in the development and control of animal tumours, particularly in those arising in their target organs. Due to their incidence and prevalence, mammary tumours of female dogs and cats are ...
    • Use of CD10 as a marker of canine mammary myoepithelial cells 

      Sánchez-Céspedes, Raquel; Suárez-Bonnet, Alejandro; Millán, Yolanda; Guil-Luna, Silvia; Reymundo, Carlos; Herráez, Pedro; Espinosa de los Monteros, Antonio; Martín de las Mulas González-Albo, Juana (Elsevier, 2013)
      CD10 is an important cell marker in the diagnosis of acute lymphoblastic leukaemia and of breast myoepithelial (ME) cells in humans. The objective of this study was to assess the value of CD10 as a marker of canine ME cells ...