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Elaboración de modelos anatómicos mediante técnicas de plastinación como alternativa al uso de animales en docencia y como recurso esencial en el proceso de enseñanza-aprendizaje
(UCOPress, 2019)
La implantación del principio de las 3Rs (Reducción, Refinamiento y Reemplazo), descritas por Russell y Burch en 1959, fue el punto de partida de numerosos cambios en la utilización de los animales, tanto en el ámbito de ...
Immunohistochemical Approach to Study Cylindrospermopsin Distribution in Tilapia (Oreochromis niloticus) under Different Exposure Conditions
(MDPI, 2014)
Cylindrospermopsin (CYN) is a cytotoxic cyanotoxin produced by several species of freshwater cyanobacteria (i.e., Aphanizomenon ovalisporum). CYN is a tricyclic alkaloid combined with a guanidine moiety. It is well known ...
Uso de N-acetilcisteína para proteger a los peces de la intoxicación por microcistinas (MCs)
(Oficina de Transferencia de Resultados de la Investigación, 2013)
La presente invención se refiere al uso de una composición que comprende N-acetilcisteína (NAC) para el tratamiento, prevención y/o recuperación de efectos tóxicos en peces expuestos a Microcistinas (MCs). También se refiere ...
Assessment of the effects of bisphenol-A as a disruptor on ionic regulation in Danio rerio zebrafish through a study of their chloride and prolactin cells
(Institute of Oceanography and Fisheries, 2017)
Bisphenol A (BPA) is one of the chemicals produced in the largest volume in the world. It is
commonly used as a component of plastics and food containers and can act as a xenoestrogen in
humans. In view of the risk of ...
Analyses of anaesthesia with ketamine combined with different sedatives in rats
(Czech Academy of Agricultural Sciences, 2015)
The goal of this study was to establish an easy-to-perform, reliable, and safe protocol for intraperitoneal injection anaesthesia in rats, as well as an easy method to assess anaesthesia depth under routine clinical ...
Evaluation of toxicological endpoints in female zebrafish after bisphenol A exposure
(Elsevier, 2018)
Given the importance of bisphenol A (BPA) as a xenoestrogen and its potential effects on human and animal, we evaluated BPA exposure's short-term effects on follicular development, yolk protein vitellogenin (VTG) production ...
Hypothalamic-pituitary-ovarian axis perturbation in the basis of bisphenol A (BPA) reproductive toxicity in female zebrafish (Danio rerio)
(Elsevier, 2018)
Thousands of safety-related studies have been published on bisphenol A (BPA), an ubiquitous environmental pollutant with estrogenic activity and many other potential biological effects. In recent years, BPA exposure has ...
Endocrine-active compound evaluation: Qualitative and quantitative histomorphological assessment of zebrafish gonads after bisphenol-A exposure
(Elsevier, 2013)
There is great social concern about the risk involved from exposure to BPA as an endocrine disrupter in
humans, as well as the possible repercussion of this chemical on the environment. In this study, the
short-term ...