Buscar
Mostrando ítems 171-180 de 195
Aglepristone decreases proliferation in progesterone receptor-positive canine mammary carcinomas
(Wiley, 2011)
Progesterone receptor (PR) antagonist aglepristone (RU534) has been used successfully for pregnancy termination and therapy of pyometra, vaginal tumors, and mammary hyperplasia in bitches and queens. All of these conditions ...
Humanized mice for the study of immunoOncology
(Elsevier, 2018)
Immunotherapy is revolutionizing cancer treatment; however, complete responses are achieved in only a small fraction of patients and tumor types. Thus, there is an urgent need for predictive preclinical models to drive ...
Expression of the Short Form of RON/STK in Feline Mammary Carcinoma
(Sage, 2019)
RON is a tyrosine kinase receptor activated by the macrophage-stimulating protein (MSP) ligand that is overexpressed in human breast cancer. In humans, RON protein can be present in different isoforms, and the most studied ...
Activation of estrogen receptor-α induces gonadotroph progesterone receptor expression and action differently in young and middle-aged ovariectomized rats
(Oxford Academic, 2009)
BACKGROUND: We attempted to define the effect of estrogen receptor (ER)α activation on gonadotroph progesterone receptor (PR) expression (mRNA and protein) and action (GnRH-stimulated and GnRH self-priming) in short- and ...
Isolation, purification, culture and characterisation of myoepithelial cells from normal and neoplastic canine mammary glands using a magnetic-activated cell sorting separation system
(Elsevier, 2013)
Mammary gland tumours, the most common malignant neoplasm in bitches, often display myoepithelial (ME) cell proliferation. The aim of this study was to isolate, purify, culture and characterise ME cells from normal and ...
Use of CD10 as a marker of canine mammary myoepithelial cells
(Elsevier, 2013)
CD10 is an important cell marker in the diagnosis of acute lymphoblastic leukaemia and of breast myoepithelial (ME) cells in humans. The objective of this study was to assess the value of CD10 as a marker of canine ME cells ...
Red and White Wine Lees show inhibitory effects on liver carcinogenesis
(Wiley, 2019-05)
Scope: Wine has shown anticarcinogenic benefits in hepatocarcinoma and
polyphenols seem to be responsible for these effects. Wine lees are the
sediments produced during fermentation and they endow wine with
organoleptic ...
Prognostic impact of neoadjuvant aglepristone treatment in clinicopathological parameters of progesterone receptor-positive canine mammary carcinomas
(Wiley, 2017)
Neoadjuvant treatment of canine mammary carcinomas with the progesterone receptor (PR) antagonist aglepristone has a PR expression-related inhibiting effect on proliferation index (PI). The aim of this study was to evaluate ...
Myoepithelial cells in canine mammary tumours
(Elsevier, 2016)
Mammary tumours are the most common neoplasms of female dogs. Compared to mammary tumours of humans and cats, myoepithelial (ME) cell involvement is common in canine mammary tumours (CMT) of any subtype. Since ME cell ...
Expression of oestrogen and progesterone receptor in canine sebaceous gland tumours
(Wiley, 2010)
Sebaceous gland oestrogen α (ERα) and progesterone (PR) receptor expression was examined immunohistochemically in 26 and 32 dogs respectively with sebaceous gland hyperplasia/adenomas, epitheliomas and carcinomas, and in ...