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Covalent Immobilization of Antibodies through Tetrazine-TCO Reaction to Improve Sensitivity of ELISA Technique
(MDPI, 2021)
Enzyme-linked immunosorbent assay (ELISA) is routinely used to detect biomolecules related to several diseases facilitating diagnosis and monitoring of these, as well as the possibility of decreasing their mortality rate. ...
CCN2 Binds to Tubular Epithelial Cells in the Kidney
(MDPI, 2022)
Cellular communication network-2 (CCN2), also called connective tissue growth factor (CTGF), is considered a fibrotic biomarker and has been suggested as a potential therapeutic target for kidney pathologies. CCN2 is a ...
Extrahypothalamic Control of Energy Balance and Its Connection with Reproduction: Roles of the Amygdala
(MDPI, 2021)
Body energy and metabolic homeostasis are exquisitely controlled by multiple, often overlapping regulatory mechanisms, which permit the tight adjustment between fuel reserves, internal needs, and environmental (e.g., ...
Detrimental Effect of Cannabidiol on the Early Onset of Diabetic Nephropathy in Male Mice
(MDPI, 2021)
Anti-inflammatory and antidiabetogenic properties have been ascribed to cannabidiol (CBD). CBD-based medicinal drugs have been approved for over a lustrum, and a boom in the commercialization of CBD products started in ...
Beef from Calves Finished with a Diet Based on Concentrate Rich in Agro-Industrial By-Products: Acceptability and Quality Label Preferences in Spanish Meat Consumers
(MDPI, 2021)
Conjoint analysis was used to estimate the relative importance of some of the main extrinsic attributes and quality labels of beef in three Spanish cities (Córdoba, Marbella, and Santa Pola) in a study performed with 300 ...
Papel etiopatogénico e implicaciones diagnósticas de microRNAs en el síndrome de ovario poliquístico
(Universidad de Córdoba, UCOPress, 2022)
1. Introducción o motivación de la tesis: El síndrome de ovario poliquístico (SOP) es una enfermedad de alta prevalencia que afecta al 5-10% del total de mujeres en edad reproductiva, cuyos síntomas se inician habitualmente ...
Sistemas de detección ultrasensible de moléculas de distinta naturaleza para la detección temprana del cáncer
(Universidad de Córdoba, UCOPress, 2022)
La técnica ELISA (del inglés “enzyme-linked immunosorbent assay”) es el método de rutina más utilizado y fiable para la detección de marcadores proteicos relevantes en la asistencia sanitaria. Aumentar la sensibilidad de ...
Functional Changes of T-Cell Subsets with Age and CMV Infection
(MDPI, 2021)
Cytomegalovirus (CMV) latent infection and aging contribute to alterations in the function and phenotype of the T-cell pool. We have demonstrated that CMV-seropositivity is associated with the expansion of polyfunctional ...
Characterization of the DNAM-1, TIGIT and TACTILE Axis on Circulating NK, NKT-Like and T Cell Subsets in Patients with Acute Myeloid Leukemia
(MDPI, 2020)
Background: Acute myeloid leukemia (AML) remains a major clinical challenge due to poor overall survival, which is even more dramatic in elderly patients. TIGIT, an inhibitory receptor that interacts with CD155 and CD112 ...
Evaluation of Two Equations for Prediction of Digestible Energy in Mixed Feeds and Diets for Horses
(MDPI, 2022)
Several authors have developed equations for estimating digestible energy in horse feeds as an alternative to the inconveniences of in vivo digestibility assays. We aimed to evaluate two of such equations. A dataset was ...