Listar por autor "12bd7fe9-d85f-4545-8315-40d8ba1cb5b6"

Mostrando ítems 1-6 de 6

    • Clinical Utility of microRNAs in Exhaled Breath Condensate as Biomarkers for Lung Cancer 

      Pérez Sánchez, Carlos; Barbarroja, Nuria; Pantaleão, Lucas C.; López-Sánchez, Laura M.; Ozanne, Susan E.; Jurado-Gámez, Bernabé; Jurado-Gámez, Bernabé; Aranda Aguilar, Enrique; López-Pedrera, Ch.; Rodríguez-Ariza, Antonio (MDPI, 2021)
      This study represents a novel proof of concept of the clinical utility of miRNAs from exhaled breath condensate (EBC) as biomarkers of lung cancer (LC). Genome-wide miRNA profiling and machine learning analysis were performed ...

    • Effects of Biological Therapies on Molecular Features of Rheumatoid Arthritis 

      López-Pedrera, Ch.; Barbarroja, Nuria; Patiño-Trives, Alejandra Mª; Luque-Tévar, María; Collantes Estévez, Eduardo; Escudero Contreras, Alejandro; Pérez Sánchez, Carlos (MDPI, 2020)
      Rheumatoid arthritis (RA) is an autoimmune and chronic inflammatory disease primarily affecting the joints, and closely related to specific autoantibodies that mostly target modified self-epitopes. Relevant findings in the ...

    • Expression of DDX11 and DNM1L at the 12p11 Locus Modulates Systemic Lupus Erythematosus Susceptibility 

      Saeed, Mohammad; Ibáñez-Costa, Alejandro; Patiño-Trives, Alejandra Mª; Muñoz-Barrera, Laura; Collantes Estévez, Eduardo; Aguirre, María Ángeles; López-Pedrera, Ch. (MDPI, 2021)
      This study employed genetic and functional analyses using OASIS meta-analysis of multiple existing GWAS and gene-expression datasets to identify novel SLE genes. Methods: Four hundred and ten genes were mapped using SNIPPER ...

    • Preclinical Characterization of Pharmacologic NAD+Boosting as a Promising Therapeutic Approach inRheumatoid Arthritis 

      Pérez Sánchez, Carlos; Escudero Contreras, Alejandro; Cerdó, Tomás; Sánchez-Mendoza, Luz Marina; Llamas Urbano, Adrián; Arias de la Rosa, Iván; Pérez Rodríguez, Miguel; Muñoz-Barrera, Laura; Ábalos-Aguilera, María del Carmen; Barbarroja, Nuria; Calvo Gutiérrez, Jerusalém; Ortega Castro, María Rafaela; Ruiz-Vilchez, Desirée; Moreno, Juan Antonio; Burón, Isabel; González Reyes, José Antonio; López-Pedrera, Ch.; Villalba, José Manuel (Wiley, 2023)
      Objective: We analyzed NAD+ metabolism in patients with rheumatoid arthritis (RA), its association with disease activity and clinical outcomes of RA, and the therapeutic potential of pharmacologic NAD+ boosting. Methods: ...

    • The clinical and molecular cardiometabolic fingerprint of an exploratory psoriatic arthritis cohort is associated with the disease activity and differentially modulated by methotrexate and apremilast 

      Arias de la Rosa, Iván; López-Montilla, María Dolores; Román-Rodríguez, Cristobal; Pérez Sánchez, Carlos; Gómez-García, Ignacio; López Medina, Eloísa Clementina; Ladehesa-Pineda, Lourdes; Ábalos-Aguilera, María del Carmen; Ruiz, Desireé; Patiño-Trives, Alejandra Mª; Luque-Tévar, María; Añón-Oñate, Isabel; Pérez-Galán, María José; Guzmán Ruiz, R.; Malagón, María M.; López-Pedrera, Ch.; Escudero Contreras, Alejandro; Collantes Estévez, Eduardo; Barbarroja, Nuria (Wiley, 2022)
      Objectives: (1) To evaluate clinical and molecular cardiovascular disease (CVD) signs and their relationship with psoriatic arthritis (PsA) features and (2) to identify a clinical patient profile susceptible to benefit ...

    • Therapeutic Potential and Immunomodulatory Role of Coenzyme Q10 and Its Analogues in Systemic Autoimmune Diseases 

      López-Pedrera, Ch.; Villalba, José Manuel; Patiño-Trives, Alejandra Mª; Luque-Tévar, María; Barbarroja, Nuria; Aguirre, M.A.; Escudero Contreras, Alejandro; Pérez Sánchez, Carlos (MDPI, 2021)
      Coenzyme Q10 (CoQ10) is a mitochondrial electron carrier and a powerful lipophilic antioxidant located in membranes and plasma lipoproteins. CoQ10 is endogenously synthesized and obtained from the diet, which has raised ...