• Circulating Tumor Cells in Hepatocellular Carcinoma: A Comprehensive Review and Critical Appraisal 

      Espejo-Cruz, María Lola; González Rubio, Sandra; Zamora-Olaya, Javier; Amado-Torres, Víctor; Alejandre, Rafael; Sánchez-Frías, Marina; Ciria, Rubén; Mata, Manuel de la; Rodríguez-Perálvarez, Manuel; Ferrín, Gustavo (MDPI, 2021)
      Hepatocellular carcinoma (HCC) is the fifth most common neoplasm and a major cause of cancer-related death worldwide. There is no ideal biomarker allowing early diagnosis of HCC and tumor surveillance in patients receiving ...
    • Development of a prediction model for short-term remission of patients with Crohn’s disease treated with anti-TNF drugs 

      Medina-Medina, Rosario; Iglesias-Flores, Eva; Benítez, José M.; Marín-Pedrosa, Sandra; Salgueiro-Rodríguez, Isabel; Linares Luna, Clara Isabel; González Rubio, Sandra; Soto-Escribano, Pilar; Gros, Beatriz; Rodríguez-Perálvarez, Manuel; Cabriada, José L.; Chaparro, María; Gisbert, Javier P.; Chicano-Gálvez, Eduardo; Ortega, Ignacio; Ferrín, Gustavo; García-Sánchez, Valle; Aguilar-Melero, P. (MDPI, 2023)
      Therapy with anti-tumor necrosis factor (TNF) has dramatically changed the natural history of Crohn’s disease (CD). However, these drugs are not without adverse events, and up to 40% of patients could lose efficacy in the ...
    • Enumeration and Characterization of Circulating Tumor Cells in Patients with Hepatocellular Carcinoma Undergoing Transarterial Chemoembolization 

      Espejo-Cruz, María Lola; González Rubio, Sandra; Espejo, Juan J.; Zamora-Olaya, Javier; Alejandre, Rafael; Prieto-Torre, María; Linares Luna, Clara Isabel; Guerrero-Misas, Marta; Barrera-Baena, Pilar; Poyato-González, Antonio; Sánchez-Frías, Marina; Ayllón Terán, M. Dolores; Rodríguez-Perálvarez, Manuel; Mata, Manuel de la; Ferrín, Gustavo (MDPI, 2023)
      Circulating tumor cells (CTCs), and particularly circulating cancer stem cells (cCSC), are prognostic biomarkers for different malignancies and may be detected using liquid biopsies. The ex vivo culture of cCSCs would ...
    • mTOR Expression in Liver Transplant Candidates with Hepatocellular Carcinoma: Impact on Histological Features and Tumour Recurrence 

      Guerrero, Marta; Ferrín, Gustavo; Rodríguez-Perálvarez, Manuel; González Rubio, Sandra; Sánchez-Frías, Marina; Amado-Torres, Víctor; Pozo, Juan C.; Poyato, Antonio; Ciria, Rubén; Ayllón Terán, M. Dolores; Barrera, Pilar; Montero, José L.; Mata, Manuel de la (MDPI, 2019)
      (1) Background: The mammalian target of rapamycin (mTOR) pathway activation is critical for hepatocellular carcinoma (HCC) progression. We aimed to evaluate the mTOR tissue expresión in liver transplant (LT) patients and ...
    • Regulación de NOS-3 durante la muerte hepatocelular inducida por ácidos biliares 

      González Rubio, Sandra (Universidad de Córdoba, UCOPress, 2017)
      1. Introducción o motivación de la tesis. La enfermedad hepática colestásica se caracteriza por una alteración en la formación de la bilis, que viene acompañada o es causada por un defecto en la excreción de la misma hacia ...