• Circulating Tumor Cells in Hepatocellular Carcinoma: A Comprehensive Review and Critical Appraisal 

      Espejo-Cruz, María Lola; González Rubio, Sandra; Zamora-Olaya, Javier; Amado-Torres, Víctor; Alejandre, Rafael; Sánchez-Frías, Marina; Ciria, Rubén; Mata, Manuel de la; Rodríguez-Perálvarez, Manuel; Ferrín, Gustavo (MDPI, 2021)
      Hepatocellular carcinoma (HCC) is the fifth most common neoplasm and a major cause of cancer-related death worldwide. There is no ideal biomarker allowing early diagnosis of HCC and tumor surveillance in patients receiving ...
    • Enumeration and Characterization of Circulating Tumor Cells in Patients with Hepatocellular Carcinoma Undergoing Transarterial Chemoembolization 

      Espejo-Cruz, María Lola; González Rubio, Sandra; Espejo, Juan J.; Zamora-Olaya, Javier; Alejandre, Rafael; Prieto-Torre, María; Linares Luna, Clara Isabel; Guerrero-Misas, Marta; Barrera-Baena, Pilar; Poyato-González, Antonio; Sánchez-Frías, Marina; Ayllón Terán, M. Dolores; Rodríguez-Perálvarez, Manuel; Mata, Manuel de la; Ferrín, Gustavo (MDPI, 2023)
      Circulating tumor cells (CTCs), and particularly circulating cancer stem cells (cCSC), are prognostic biomarkers for different malignancies and may be detected using liquid biopsies. The ex vivo culture of cCSCs would ...
    • mTOR Expression in Liver Transplant Candidates with Hepatocellular Carcinoma: Impact on Histological Features and Tumour Recurrence 

      Guerrero, Marta; Ferrín, Gustavo; Rodríguez-Perálvarez, Manuel; González Rubio, Sandra; Sánchez-Frías, Marina; Amado-Torres, Víctor; Pozo, Juan C.; Poyato, Antonio; Ciria, Rubén; Ayllón Terán, M. Dolores; Barrera, Pilar; Montero, José L.; Mata, Manuel de la (MDPI, 2019)
      (1) Background: The mammalian target of rapamycin (mTOR) pathway activation is critical for hepatocellular carcinoma (HCC) progression. We aimed to evaluate the mTOR tissue expresión in liver transplant (LT) patients and ...