Listar por autor "f7db44dc-713f-407b-b48a-4bca98029e30"

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    • Comparative proteomic analysis of normal and NQO1-null mouse embryo fibroblasts 

      Jódar-Montilla, Laura; Santos-González, Mónica; Burón, Isabel; Alcaín Tejada, F.J.; Cabo, Rafael de; Villalba, José Manuel (Universidad de Córdoba, Servicio de Publicaciones, 2009)

    • Complex I-Associated Hydrogen Peroxide Production Is Decreased and Electron Transport Chain Enzyme Activities Are Altered in n-3 Enriched fat-1 Mice 

      Hagopian, Kevork; Weber, Kristina L.; Hwee, Darren T.; Van Eenennaam, Alison L.; López-Lluch, Guillermo; Villalba, José Manuel; Burón, Isabel; Navas Lloret, Plácido; German, Bruce; Watkins, Steven; Chen, Yana; Wei, Alfreda; McDonald, Roger B.; Ramsey, Jon J. (Public Libray of Science (PLOS), 2010)
      The polyunsaturated nature of n-3 fatty acids makes them prone to oxidative damage. However, it is not clear if n-3 fatty acids are simply a passive site for oxidative attack or if they also modulate mitochondrial reactive ...

    • CYB5R3 overexpression preserves skeletal muscle mitochondria and autophagic signaling in aged transgenic mice 

      López Bellón, Sara; Rodríguez López, Sandra; González Reyes, José Antonio; Burón, Isabel; Cabo, Rafael de; Villalba, José Manuel (Springer, 2022)
      Cytochrome b5 reductase 3 (CYB5R3) overexpression activates respiratory metabolism and exerts prolongevity effects in transgenic mice, mimicking some of the salutary effects of calorie restriction. The aim of our study was ...

    • Desarrollo de un modelo docente adaptado a los criterios metodológicos 

      Ruiz, Antonio; Gaytán, Francisco; Lucena, Concepción; Villalba, José Manuel; Vázquez Martínez, Rafael; Martínez-Fuentes, Antonio J.; Gracia-Navarro, F.; González Reyes, José Antonio; García-Navarro, Socorro; Castaño, Justo P.; Alcaín Tejada, F.J.; Burón, Isabel; Malagón, María M. (Consejo Social de la Universidad de Córdoba, 2008)

    • Experiencias en flipped learning 

      Burón, Isabel; Avendaño, S.; Cantarero, Irene; Gahete Ortiz, Manuel D.; Guzmán Ruiz, R.; Vázquez, M.J.; Luque, Rafael; Malagón, María M.; Villalba, José Manuel; Calzado Canale, Marco Antonio (UCOPress, 2018)
      El presente trabajo describe unas experiencias de innovación docente, de igual perfil y metodología, desarrolladas por un conjunto de profesores noveles participantes bajo la tutela experta de profesorado senior. El tipo ...

    • Metabolic shift underlies tumor progression and immune evasion in S-nitrosoglutathione reductase-deficient cancer 

      Mena-Osuna, Rafael; Mantrana, Ana; Guil-Luna, Silvia; Sánchez, María-Teresa; Navarrete, Carmen; Morales-Ruiz, T.; Rivas-Crespo, Aurora; Toledano-Fonseca, Marta; García-Ortíz, María Victoria; García Jurado, Gema; Gómez-España, M. Auxiliadora; González Fernández, Rafael A.; Villar, Carlos; Medina Fernández, Francisco Javier; Villalba, José Manuel; Aranda Aguilar, Enrique; Rodríguez-Ariza, Antonio (Wiley, 2023)
      S-nitrosoglutathione reductase (GSNOR) is a denitrosylase enzyme that has been suggested to play a tumor suppressor role, although the mechanisms responsible are still largely unclear. In this study, we show that GSNOR ...

    • Olive Oil and the Hallmarks of Aging 

      Fernández del Río, Lucía; Gutiérrez-Casado, Elena; Varela-López, Alfonso; Villalba, José Manuel (MDPI, 2016)
      Aging is a multifactorial and tissue-specific process involving diverse alterations regardedas the “hallmarks of aging”, which include genomic instability, telomere attrition, epigenetic alterations, loss of proteostasis, ...

    • Protective Role of Nrf2 in Renal Disease 

      Guerrero-Hue, Melania; Rayego-Mateos, Sandra; Vázquez-Carballo, Cristina; Palomino-Antolín, Alejandra; García-Caballero, Cristina; Opazo-Ríos, Lucas; Morgado-Pascual, José Luis; Herencia, Carmen; Mas, Sebastián; Ortiz, Alberto; Rubio-Navarro, Alfonso; Egea, Javier; Villalba, José Manuel; Egido, J.; Moreno, Juan Antonio (MDPI, 2020)
      Chronic kidney disease (CKD) is one of the fastest-growing causes of death and is predicted to become by 2040 the fifth global cause of death. CKD is characterized by increased oxidative stress and chronic inflammation. ...

    • Therapeutic Potential and Immunomodulatory Role of Coenzyme Q10 and Its Analogues in Systemic Autoimmune Diseases 

      López-Pedrera, Ch.; Villalba, José Manuel; Patiño-Trives, Alejandra Mª; Luque-Tévar, María; Barbarroja, Nuria; Aguirre, M.A.; Escudero Contreras, Alejandro; Pérez Sánchez, Carlos (MDPI, 2021)
      Coenzyme Q10 (CoQ10) is a mitochondrial electron carrier and a powerful lipophilic antioxidant located in membranes and plasma lipoproteins. CoQ10 is endogenously synthesized and obtained from the diet, which has raised ...