• Procaine Inhibits Osteo/Odontogenesis through Wnt/β-Catenin Inactivation 

      Herencia, Carmen; Díaz Tocados, Juan Manuel; Jurado, Lidia; Montes de Oca, Addy; Rodríguez-Ortiz, Maria E.; Martín-Alonso, Carmen; Martínez-Moreno, Julio M.; Vergara, Noemi; Rodríguez, Mariano; Almadén Peña, Yolanda; Muñoz-Castañeda, Juan R. (Public Library of Science, 2016)
      Introduction Periodontitis is a complex pathology characterized by the loss of alveolar bone. The causes and the mechanisms that promote this bone resorption still remain unknown. The knowledge of the critical regulators ...
    • Promoter DNA Hypermethylation and Gene Repression in Undifferentiated Arabidopsis Cells 

      Berdasco, María; Alcázar, Rubén; García-Ortiz, M.V.; Ballestar, Esteban; Fernández, Agustín F.; Roldán-Arjona, Teresa; Tiburcio, Antonio F.; Altabella, Teresa; Buisine, Nicolas; Quesneville, Hadi; Baudry, Antoine; Lepiniec, Loïc; Alaminos, Miguel; Rodríguez, Roberto; Lloyd, Alan; Colot, Vincent; Bender, Judith; Canal, María Jesús; Esteller, Manel; Fraga, Mario F. (Public Library of Science, 2008)
      Maintaining and acquiring the pluripotent cell state in plants is critical to tissue regeneration and vegetative multiplication. Histone-based epigenetic mechanisms are important for regulating this undifferentiated state. ...
    • TGF-β Prevents Phosphate-Induced Osteogenesis through Inhibition of BMP and Wnt/β-Catenin Pathways 

      Guerrero Pavón, Fátima; Herencia, Carmen; Almadén Peña, Yolanda; Martínez-Moreno, Julio M.; Montes de Oca, Addy; Rodríguez-Ortiz, Maria E.; Díaz Tocados, Juan Manuel; Florio, Mónica; López, Ignacio; Richards, William G.; Rodríguez Portillo, Mariano; Aguilera Tejero, Escolástico; Muñoz-Castañeda, Juan R. (Public Library of Science, 2014)
      Background: Transforming growth factor-b (TGF-b) is a key cytokine during differentiation of mesenchymal stem cells (MSC) into vascular smooth muscle cells (VSMC). High phosphate induces a phenotypic transformation of ...