ListarDepartamento de Ciencias Médicas y Quirúrgicas por tema "Gene expression"

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    • Effect of 8-Week Consumption of a Dietary Pattern Based on Fruit, Avocado, Whole Grains, and Trout on Postprandial Inflammatory and Oxidative Stress Gene Expression in Obese People 

      López-Miranda, José; Muñoz-Pérez, Diana María; González-Correa, Clara Helena; Astudillo-Muñoz, Elcy Yaned; Sánchez-Giraldo, Maite; Carmona-Hernández, Juan Carlos; López-Miranda, José; Camargo García, A.; Rangel Zúñiga, Oriol Alberto (MDPI, 2023)
      Overweight and obesity constitute a major global public health problem. Healthy dietary patterns induce changes at the molecular level. Currently, there are no studies evaluating the effect of a diet based on fruit, avocado, ...

    • Effects of rs7903146 Variation in the Tcf7l2 Gene in the Lipid Metabolism of Three Different Populations 

      Pérez-Caballero, Ana I.; García-Ríos, Antonio; Gómez-Luna, María J.; Gómez-Luna, Purificación; Dembinska-Kiec, Aldona; Rodríguez-Cantalejo, Fernando; Camargo García, A.; Marín, Carmen; Pérez-Martínez, Pablo; Delgado-Lista, Javier; Yubero-Serrano, Elena M.; Tinahones, Francisco J.; Pérez-Jiménez, Francisco; Roche, Helen M.; López-Miranda, José (Public Library Of Science (PLOS), 2012)
      Background: TCF7L2 rs7903146 is an important genetic factor predicting type 2 diabetes (T2DM) which has also been linked to higher cardiovascular risk. To date, there is little information about the additional impact of ...

    • Magnesium Inhibits Wnt/β-Catenin Activity and Reverses the Osteogenic Transformation of Vascular Smooth Muscle Cells 

      Montes de Oca, Addy; Guerrero Pavón, Fátima; Martínez-Moreno, Julio M.; Madueño, Juan A.; Herencia, Carmen; Peralta, Alan; Almadén Peña, Yolanda; López, Ignacio; Aguilera Tejero, Escolástico; Gundlach, Kristina; Büchel, Janine; Peter, Mirjam E.; Passlick-Deetjen, Jutta; Rodríguez Portillo, Mariano; Muñoz-Castañeda, Juan R. (Public Library of Science, 2014)
      Magnesium reduces vascular smooth muscle cell (VSMC) calcification in vitro but the mechanism has not been revealed so far. This work used only slightly increased magnesium levels and aimed at determining: a) whether ...

    • Transcriptomic Coordination in the Human Metabolic Network Reveals Links between n-3 Fat Intake, Adipose Tissue Gene Expression and Metabolic Health 

      Morine, Melissa J.; Tierney, Audrey C.; Van Ommen, Ben; Daniel, Hannelore; Toomey, Sinead; Gjelstad, Ingrid M.F.; Gormley, Isobel C.; Drevon, Christian A.; Pérez-Martínez, Pablo; Roche, Helen M.; López-Miranda, José (Public Library Of Science (PLOS), 2011)
      Understanding the molecular link between diet and health is a key goal in nutritional systems biology. As an alternative to pathway analysis, we have developed a joint multivariate and network-based approach to analysis ...