ListarDepartamento de Ciencias Médicas y Quirúrgicas por tema "Metabolism"

Mostrando ítems 1-3 de 3

    • Metabolic shift underlies tumor progression and immune evasion in S-nitrosoglutathione reductase-deficient cancer 

      Mena-Osuna, Rafael; Mantrana, Ana; Guil-Luna, Silvia; Sánchez, María-Teresa; Navarrete, Carmen; Morales-Ruiz, T.; Rivas-Crespo, Aurora; Toledano-Fonseca, Marta; García-Ortíz, María Victoria; García Jurado, Gema; Gómez-España, M. Auxiliadora; González Fernández, Rafael A.; Villar, Carlos; Medina Fernández, Francisco Javier; Villalba, José Manuel; Aranda Aguilar, Enrique; Rodríguez-Ariza, Antonio (Wiley, 2023)
      S-nitrosoglutathione reductase (GSNOR) is a denitrosylase enzyme that has been suggested to play a tumor suppressor role, although the mechanisms responsible are still largely unclear. In this study, we show that GSNOR ...

    • Targeting metabolism to improve immunotherapy in gsnor-deficient colorectal cancer 

      Mantrana, Ana (Universidad de Córdoba, UCOPress, 2024)
      Colorectal cancer (CRC) is the third most diagnosed type of cancer and the second leading cause of cancer death worldwide. Despite the increasing knowledge of CRC molecular biology and the development of new targeted ...

    • Transcriptomic Coordination in the Human Metabolic Network Reveals Links between n-3 Fat Intake, Adipose Tissue Gene Expression and Metabolic Health 

      Morine, Melissa J.; Tierney, Audrey C.; Van Ommen, Ben; Daniel, Hannelore; Toomey, Sinead; Gjelstad, Ingrid M.F.; Gormley, Isobel C.; Drevon, Christian A.; Pérez-Martínez, Pablo; Roche, Helen M.; López-Miranda, José (Public Library Of Science (PLOS), 2011)
      Understanding the molecular link between diet and health is a key goal in nutritional systems biology. As an alternative to pathway analysis, we have developed a joint multivariate and network-based approach to analysis ...