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Effects of rs7903146 Variation in the Tcf7l2 Gene in the Lipid Metabolism of Three Different Populations
(Public Library Of Science (PLOS), 2012)
Background: TCF7L2 rs7903146 is an important genetic factor predicting type 2 diabetes (T2DM) which has also been linked
to higher cardiovascular risk. To date, there is little information about the additional impact of ...
Proteome from patients with metabolic syndrome is regulated by quantity and quality of dietary lipids
(BioMed Central, 2015)
Background: Metabolic syndrome is a multi-component disorder associated to a high risk of cardiovascular disease.
Its etiology is the result of a complex interaction between genetic and environmental factors, including ...
Influence of Obesity and Metabolic Disease on Carotid Atherosclerosis in Patients with Coronary Artery Disease (CordioPrev Study)
(Public Library of Science, 2016)
Background
Recent data suggest that the presence of associated metabolic abnormalities may be
important modifiers of the association of obesity with a poorer prognosis in coronary heart
disease. We determined the influence ...
A plasma fatty acid profile associated to type 2 diabetes development: from the CORDIOPREV study
(Springer, 2021)
Purpose: The prevalence of type 2 diabetes mellitus (T2DM) is increasing worldwide. For this reason, it is essential to identify biomarkers for the early detection of T2DM risk and/or for a better prognosis of T2DM. We ...
Diet and SIRT1 Genotype Interact to Modulate Aging-Related Processes in Patients with Coronary Heart Disease: From the CORDIOPREV Study
(MDPI, 2022)
We investigated whether long-term consumption of two healthy diets (low-fat (LF) or Mediterranean (Med)) interacts with SIRT1 genotypes to modulate aging-related processes such as leucocyte telomere length (LTL), oxidative ...
Long-term effect of a dietary intervention with two-healthy dietary approaches on food intake and nutrient density in coronary patients: results from the CORDIOPREV trial
(Springer, 2022)
Background: Cardiovascular disease (CVD) is the leading cause of disease burden in the world by non-communicable diseases. Nutritional interventions promoting high-quality dietary patterns with low caloric intake value and ...
Beta cell functionality and hepatic insulin resistance are major contributors to type 2 diabetes remission and starting pharmacological therapy: from CORDIOPREV randomized controlled trial
(Elsevier, 2021)
In order to assess whether previous hepatic IR (Hepatic-IR fasting) and beta-cell functionality could modulate type 2 diabetes remission and the need for starting glucose- lowering treatment, newly-diagnosed type 2 diabetes ...
Hypertriglyceridemia Influences the Degree of Postprandial Lipemic Response in Patients with Metabolic Syndrome and Coronary Artery Disease: From the Cordioprev Study
(PLOS, 2014)
Objective
To determine whether metabolic syndrome traits influence the postprandial lipemia response of coronary patients, and whether this influence depends on the number of MetS criteria.
Materials and Methods
1002 ...