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Adult primary paratesticular mesenchymal tumors with emphasis on a case presentation and discussion of spermatic cord leiomyosarcoma
dc.contributor.author | Galosi, Andrea B. | |
dc.contributor.author | Scarpelli, Marina | |
dc.contributor.author | Mazzucchelli, Roberta | |
dc.contributor.author | López-Beltrán, Antonio | |
dc.contributor.author | Giustini, Lucio | |
dc.contributor.author | Cheng, Liang | |
dc.contributor.author | Montironi, Rodolfo | |
dc.date.accessioned | 2017-01-18T12:37:02Z | |
dc.date.available | 2017-01-18T12:37:02Z | |
dc.date.issued | 2014 | |
dc.identifier.uri | http://hdl.handle.net/10396/14328 | |
dc.description.abstract | Background: The aim of this report is related to adult primary paratesticular mesenchymal tumors with emphasis on a case presentation and discussion of the spermatic cord leiomyosarcoma. Primary paratesticular tumors are rare, only accounting for 7% to 10% of all intrascrotal tumors. In adults, more than 75% of these lesions arise from the spermatic cord, 20% being leiomyosarcoma. Tumor grade, stage, histologic type, and lymph node involvement are independently predictive of prognosis. Findings: The case report concerns a 81-year-old man presented with a 3-year history of painless lump in the right hemiscrotum. Scrotal examination demonstrated a 5.1-cm, firm-to-hard mass attached to the spermatic cord. Scrotal ultrasound scan revealed a heterogeneous mass separate from the testis. He was treated with an radical orchi-funicolectomy. Histologically the lesion is composed of spindled cells with often elongated, blunt-ended nuclei and variably eosinophilic cytoplasm. Areas with pleomorphic morphology are present. The level of mitotic activity is equal to 3/10 HPF in the areas with spindle cell morphology and to 12/10 HPF in the areas with pleomorphic morphology. The final diagnosis was that a leiomyosarcoma of the spermatic cord, with grade 1 and grade 2 areas, stage pT2b cN0 and cM0. The patient has been followed up for 3 months with CT scans and shows no signs of recurrence. Conclusions: Spermatic cord leiomyosarcoma, although rare, should be one of the first differential diagnoses for a firm-to-hard lump in the cord. Apart from radical orchi-funicolectomy, there has been added benefit of adjuvant radiotherapy to prevent any loco-regional lymph node recurrence | es_ES |
dc.format.mimetype | application/pdf | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | BioMed Central | es_ES |
dc.rights | https://creativecommons.org/licenses/by-nc-nd/4.0/ | es_ES |
dc.source | Diagnostic Pathology, 9:90 (2014) | es_ES |
dc.subject | Leiomyosarcoma of the spermatic cord | es_ES |
dc.subject | Mesenchymal tumors of the scrotum | es_ES |
dc.subject | Spermatic cord | es_ES |
dc.subject | Liposarcoma | es_ES |
dc.subject | Rhabdomyosarcoma | es_ES |
dc.title | Adult primary paratesticular mesenchymal tumors with emphasis on a case presentation and discussion of spermatic cord leiomyosarcoma | es_ES |
dc.type | info:eu-repo/semantics/article | es_ES |
dc.relation.publisherversion | http://www.diagnosticpathology.org/content/9/1/90 | es_ES |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | es_ES |