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Thioredoxin Downregulation Enhances Sorafenib Effects in Hepatocarcinoma Cells
López-Grueso, María José; González, Raúl; Muntané Relat, Jordi; Bárcena Ruiz, José Antonio; Padilla, Alicia (MDPI, 2019)Sorafenib is the first-line recommended therapy for patients with advanced hepatocarcinoma (HCC) in de-differentiation stage (presenting epithelial–mesenchymal transition, EMT). We studied the role of the thioredoxin system ...