Listar Artículos, capítulos, libros...UCO por autor "2ade28b3-8303-49fb-aece-473726949953"
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Glomerular Hematuria: Cause or Consequence of Renal Inflammation?
Moreno, Juan Antonio; Sevillano, Ángel; Gutiérrez, Eduardo; Guerrero-Hue, Melania; Vázquez-Carballo, Cristina; Yuste, Claudia; Herencia, Carmen; García-Caballero, Cristina; Praga, Manuel; Egido, J. (MDPI, 2019)Glomerular hematuria is a cardinal symptom of renal disease. Glomerular hematuria may be classified as microhematuria or macrohematuria according to the number of red blood cells in urine. Recent evidence suggests a ... -
Lipotoxicity and Diabetic Nephropathy: Novel Mechanistic Insights and Therapeutic Opportunities
Opazo-Ríos, Lucas; Mas, Sebastián; Marín-Royo, Gema; Mezzano, Sergio; Gómez-Guerrero, Carmen; Moreno, Juan Antonio; Egido, J. (MDPI, 2020)Lipotoxicity is characterized by the ectopic accumulation of lipids in organs different from adipose tissue. Lipotoxicity is mainly associated with dysfunctional signaling and insulin resistance response in non-adipose ... -
Protective Role of Nrf2 in Renal Disease
Guerrero-Hue, Melania; Rayego-Mateos, Sandra; Vázquez-Carballo, Cristina; Palomino-Antolín, Alejandra; García-Caballero, Cristina; Opazo-Ríos, Lucas; Morgado-Pascual, José Luis; Herencia, Carmen; Mas, Sebastián; Ortiz, Alberto; Rubio-Navarro, Alfonso; Egea, Javier; Villalba, José Manuel; Egido, J.; Moreno, Juan Antonio (MDPI, 2020)Chronic kidney disease (CKD) is one of the fastest-growing causes of death and is predicted to become by 2040 the fifth global cause of death. CKD is characterized by increased oxidative stress and chronic inflammation. ... -
Role of Toll-like receptor 4 in intravascular hemolysis-mediated injury
Vázquez-Carballo, Cristina; Herencia, Carmen; Guerrero-Hue, Melania; García-Caballero, Cristina; Rayego-Mateos, Sandra; Morgado-Pascual, José Luis; Opazo-Ríos, Lucas; González-Guerrero, Cristian; Vallejo-Mudarra, Mercedes; Cortegano, Isabel; Gaspar, María Luisa; Andrés, Belén de; Egido, J.; Moreno, Juan Antonio (Wiley, 2022)Massive intravascular hemolysis is a common characteristic of several pathologies. It is associated with the release of large quantities of heme into the circulation, promoting injury in vulnerable organs, mainly kidney, ... -
Semaglutide improves liver steatosis and de novo lipogenesis markers in obese and type-2-diabetic mice with metabolic-dysfunction-associated steatotic liver disease
Soto-Catalán, Manuel; Opazo-Ríos, Lucas; Quiceno, Hernán; Lázaro, Iolanda; Moreno, Juan Antonio; Gómez-Guerrero, Carmen; Egido, J.; Mas-Fontao, Sebastián (MDPI, 2024)Metabolic-dysfunction-associated steatotic liver disease (MASLD) is a prevalent clinical condition associated with elevated morbidity and mortality rates. Patients with MASLD treated with semaglutide, a glucagon-like ... -
The chronic intake of a Mediterranean diet enriched in virgin olive oil, decreases nuclear transcription factor kappaB activation in peripheral blood mononuclear cells from healthy men
Pérez Martínez, Pablo; López Miranda, José; Blanco-Colio, Luis M.; Bellido, Cecilia; Jiménez, Yolanda; Moreno, Juan; Delgado-Lista, Javier; Egido, J.; Pérez Jiménez, Francisco (Elsevier, 2007)Objetive Nuclear transcription factor κB (NF-κB) plays a key role in the inflammatory response and can be modulate by dietary fat. We have examined the effect of three diets, with different fat composition, on the activation ...