• A Straightforward Cytometry-Based Protocol for the Comprehensive Analysis of the Inflammatory Valve Infiltrate in Aortic Stenosis 

      Álvarez-Heredia, Pablo; Domínguez-del-Castillo, José Joaquín; Reina-Alfonso, Irene; Gutiérrez-González, Carmen; Hassouneh, Fakhri; Batista-Duharte, Alexander; Trujillo-Aguilera, Antonio; López-Romero, Rosalía; Muñoz, Ignacio; Pera, Alejandra (MDPI, 2023)
      Aortic stenosis (AS) is a frequent cardiac disease in old individuals, characterized by valvular calcification, fibrosis, and inflammation. Recent studies suggest that AS is an active inflammatory atherosclerotic-like ...
    • Immune Checkpoint Inhibitors for Vaccine Improvements: Current Status and New Approaches 

      Batista-Duharte, Alexander; Hassouneh, Fakhri; Álvarez-Heredia, Pablo; Pera, Alejandra; Solana Lara, Rafael (MDPI, 2022)
      In recent years, the use of immune checkpoint inhibitors (ICIs) in combination with approved or experimental vaccines has proven to be a promising approach to improve vaccine immunogenicity and efficacy. This strategy seeks ...
    • Spanish HCMV Seroprevalence in the 21st Century 

      Álvarez-Heredia, Pablo; Reina-Alfonso, Irene; Domínguez-del-Castillo, José Joaquín; Hassouneh, Fakhri; Gutiérrez-González, Carmen; Batista-Duharte, Alexander; Pérez, Ana Belén; Sarramea, Fernando; Jaén Moreno, María José; Camacho-Rodríguez, Cristina; Tarazona, Raquel (MDPI, 2024)
      Human cytomegalovirus (HCMV) is linked to age-related diseases like cardiovascular disease, neurodegenerative conditions, and cancer. It can also cause congenital defects and severe illness in immunocompromised individuals. ...